1042105-86-1

Basic information

• Product Name: tert-butyl [(1R)-3-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate
• Synonyms: tert-butyl [(1R)-3-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate
• CAS NO: 1042105-86-1
• Molecular Weight: 521.463
• Mol File: 1042105-86-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl [(1R)-3-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [(1R)-3-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate(1042105-86-1)
• EPA Substance Registry System: tert-butyl [(1R)-3-[(8S)-8-methyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate(1042105-86-1)

Safety Data

• Hazardous Substances Data: 1042105-86-1(Hazardous Substances Data)

Upstream product

• 762240-93-7 8-methyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 
• 486460-00-8 (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 
• 611240-66-5 8-methyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine 
• 611240-53-0 C₁₅H₁₈F₃NO₄ 

Relevant articles and documents

Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from β-aminoamides bearing subsituted triazolopiperazines

A series of β-aminoamides bearing triazolopiperazines have been discovered as potent, selective, and orally active dipeptidyl peptidase IV (DPP-4) inhibitors by extensive structure-activity relationship (SAR) studies around the triazolopiperazine moiety.