1042159-88-5Relevant academic research and scientific papers
Semi-synthesis and proteasome inhibition of D-ring deoxy analogs of (-)-epigallocatechin gallate (EGCG), the active ingredient of green tea extract
Huo, Congde,Shi, Guoqing,Lam, Wai Har,Chen, Di,Cui, Quizhi Cindy,Dou, Q. Ping,Chan, Tak Hang
, p. 495 - 502 (2008/09/21)
A semi-synthetic route to the D-ring analogs of (-)-epigallocatechin gallate (EGCG) from the relatively abundant (-)-epigallocatechin (EGC), isolated from, green tea leaves, is described. A natural product (13), found in Cistus salvifolius, its acetate (14) and analog (17) were synthesized by this method. Their inhibitory activities against proteasomes were investigated.
