1042303-85-4Relevant articles and documents
The highly enantioselective Michael addition of ketones to nitrodienes catalyzed by the efficient organocatalyst system of pyrrolidinyl-thioimidazole and chiral thioureido acid
Li, Zhao-Bo,Luo, Shu-Ping,Guo, Yi,Xia, Ai-Bao,Xu, Dan-Qian
supporting information; experimental part, p. 2505 - 2508 (2010/08/07)
The highly enantioselective Michael addition reaction of ketones to nitrodienes was promoted efficiently by the accessible and fine-tunable organocatalytic system of pyrrolidinyl-thioimidazole and chiral thioureido acid. The corresponding adducts were afforded in good yields with high diastereoselectivities (up to 99:1) and excellent enantioselectivities (up to 99% ee). The Royal Society of Chemistry 2010.