104239-16-9Relevant academic research and scientific papers
A Synthesis of 2-Alkyl and 2-Benzyl Substituted Acrylonitriles from 2-Alkyl and 2-Benzylidene Cyanoacetate Esters Under Mild Conditions
Cushman, Mark,Jurayj, Jurjus
, p. 1463 - 1468 (2007/10/02)
Substituted cyanoacetate esters were reduced with sodium borohydride to give good yields of the corresponding β-hydroxynitriles, which were converted to 2-substituted acrylonitriles by base catalysed elimination of their sulfonate esters.
A New Simple Synthesis of α-Substituted Acrylonitriles
Baraldi, P. G.,Pollini, G. P.,Zanirato, V.,Barco, A.,Benetti, S.
, p. 969 - 970 (2007/10/02)
An efficient preparation of α-substituted acrylonitriles 6 based on the utilization of 4-cyano-3-ketothiolane enolate anion (3) as a synthetic equivalent to α-acrylonitrile anion (1) is described.
