1042443-44-6Relevant academic research and scientific papers
4-Methyl-5-phenyl triazoles as selective inhibitors of 11β-hydroxysteroid dehydrogenase type I
Zhu, Yuping,Olson, Steven H.,Hermanowski-Vosatka, Anne,Mundt, Steven,Shah, Kashmira,Springer, Marty,Thieringer, Rolf,Wright, Samuel,Xiao, Jianying,Zokian, Hratch,Balkovec, James M.
scheme or table, p. 3405 - 3411 (2009/04/07)
4-Methyl-5-phenyl-(1,2,4)-triazoles were identified as selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). They were active in vitro and in an in vivo mouse pharmacodynamic (PD) model. The synthesis and structure activity relations
