104261-79-2

Basic information

• Product Name: (S)2,3-DIHYDRO-INDOLE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER
• Synonyms: (S)2,3-DIHYDRO-INDOLE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER;(S)-N-(benzyloxycarbonyl)indoline-2-carboxylic acid;N-Cbz-(S)-indoline-2-carboxylic acid;(S)-1-((benzyloxy)carbonyl)indoline-2-carboxylic acid
• CAS NO: 104261-79-2
• Molecular Formula: C₁₇H₁₅NO₄
• Molecular Weight: 297.31
• Mol File: 104261-79-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 117-118 °C
• Boiling Point: 499.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.350±0.06 g/cm3(Predicted)
• PKA: 3.85±0.20(Predicted)
• CAS DataBase Reference: (S)2,3-DIHYDRO-INDOLE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (S)2,3-DIHYDRO-INDOLE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER(104261-79-2)
• EPA Substance Registry System: (S)2,3-DIHYDRO-INDOLE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER(104261-79-2)

Safety Data

• Hazardous Substances Data: 104261-79-2(Hazardous Substances Data)

Usage

General Description

(S)-2,3-dihydro-indole-1,2-dicarboxylic acid 1-benzyl ester is a chemical compound with a molecular formula C18H17NO4. It is a benzyl ester derivative of the indole-1,2-dicarboxylic acid and has potential pharmaceutical applications due to its ability to interact with biological systems. The compound is a white to off-white crystalline solid with a melting point of approximately 115-117°C. It is used in scientific research and drug development as a building block for the synthesis of various biologically active molecules and pharmaceuticals. The exact biological and pharmacological properties and applications of (S)-2,3-dihydro-indole-1,2-dicarboxylic acid 1-benzyl ester are areas of ongoing research and exploration.

Upstream product

• 79815-20-6 (S)-indoline-2-carboxylic acid 
• 501-53-1 benzyl chloroformate 
• 135829-03-7 methyl (+/-)-1-benzyloxycarbonyl-indoline-2-carboxylate 
• 763047-58-1 (R)-indoline-carboxylic acid 

Downstream Products

• 200644-41-3 methyl (S)-1-benzyloxycarbonyl-indoline-2-carboxylate 
• 220648-65-7 (S)-1-pyrrolidine 
• 220648-66-8 (S)-4-morpholine 
• 220648-67-9 (S)-4-methyl-1-piperazine 
• 220648-68-0 (S)-4-benzyl-1-piperazine 
• 185213-04-1 N-benzyloxycarbonyl-(2S)-indolinecarboxylic acid propylamide 
• 185213-12-1 N-benzyloxycarbonyl-(2S)-indolinecarboxylic acid ethylamide 
• 185213-00-7 N-benzyloxycarbonyl-(2S)-indolinecarboxylic acid n-butylamide 
• 185213-08-5 N-benzyloxycarbonyl-(2S)-indolinecarboxylic acid methylamide 
• 946570-87-2 (S)-1-(benzyloxycarbonyl)indoline-2-carboxamide 
• 946570-88-3 (S)-1-(benzyloxycarbonyl)indoline-2-carbonitrile 
• 946570-89-4 5-[(S)-1-(benzyloxycarbonyl)indolin-2-yl]tetrazole 
• 185213-09-6 (2S)-indolinecarboxylic acid methylamide 
• 185213-10-9 N-benzyloxycarbonyl-(2S)-aminobutyryl-(2S)-indolinecarboxylic acid methylamide 

Relevant articles and documents

On the origins of enantioselectivity in oxazaborolidine mediated carbonyl reductions

A series of tricyclic oxazaborolidine catalysts have been prepared from readily available (S)-indoline-2-carboxylic acid. In each case, an arene chromium(0) carbonyl group was introduced on one face of the catalyst. Results obtained in the borane mediated

ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS

The present invention provides indoline heterocyclic compounds of the following formula I: or pharmaceutically acceptable salts, prodrugs, solvates, or hydrates thereof useful as antibacterial agents, pharmaceutical compositions containing them, methods f

Tetrazolic acid functionalized dihydroindol: Rational design of a highly selective cyclopropanation organocatalyst

(Chemical Equation Presented) Herein we wish to report our development of an improved catalyst (S)-(-)-indoline-2-yl-1H-tetrazole (1) for the enantioselective organocatalyzed cyclopropanation of α,β-unsaturated aldehydes with sulfur ylides. The new organo