1042679-29-7

Basic information

• Product Name: C₁₈H₁₉ClN₂O₂
• CAS NO: 1042679-29-7
• Molecular Weight: 330.814
• Mol File: 1042679-29-7.mol

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₉ClN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₉ClN₂O₂(1042679-29-7)
• EPA Substance Registry System: C₁₈H₁₉ClN₂O₂(1042679-29-7)

Safety Data

• Hazardous Substances Data: 1042679-29-7(Hazardous Substances Data)

Upstream product

• 220634-41-3 4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran 
• 104-12-1 p-chlorphenylisocyanate 

Relevant articles and documents

Synthesis and activity on rat aorta rings and rat pancreatic β-cells of ring-opened analogues of benzopyran-type potassium channel activators

Ring-opened analogues of dihydrobenzopyran potassium channel openers (PCOs) were prepared and evaluated as putative PCOs on rat aorta rings (myorelaxant effect) and rat pancreatic β-cells (inhibition of insulin secretion). These derivatives are characterized by the presence of a sulfonylurea, a urea or an amide function. Some compounds bearing an arylurea moiety provoked vasorelaxant effects and a marked inhibition of insulin release. Derivatives bearing a sulfonylurea or an amide function were, however, poorly active on both tissues. Structure-activity relationships and apparent tissue selectivity are discussed.