104281-91-6

Upstream product

• 108-31-6 maleic anhydride 
• 104281-87-0 2-<1-hydroxy-1-(3,4,5-trimethoxyphenyl)methyl>-4,5-dimethoxybenzyltrimethylsilane 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 83392-72-7 (2-bromo-4,5-dimethoxybenzyl)trimethylsilane 

Downstream Products

• 110410-89-4 (1S,2R,3R)-6,7-Dimethoxy-1-(3,4,5-trimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalene-2,3-dicarboxylic acid 2-methyl ester 
• 110410-88-3 (1S,2S,3S)-6,7-Dimethoxy-1-(3,4,5-trimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalene-2,3-dicarboxylic acid 3-methyl ester 
• 110410-89-4 (1S,2S,3R)-6,7-Dimethoxy-1-(3,4,5-trimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalene-2,3-dicarboxylic acid 2-methyl ester 
• 110410-88-3 (1S,2S,3R)-6,7-Dimethoxy-1-(3,4,5-trimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalene-2,3-dicarboxylic acid 3-methyl ester 
• 110410-92-9 (3aR,4S,9aR)-6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3a,4,9,9a-tetrahydro-3H-naphtho[2,3-c]furan-1-one 
• 1176-70-1 deoxysikkimotoxin 
• 96370-01-3 (1R,2R,3R)-3-Hydroxymethyl-6,7-dimethoxy-1-(3,4,5-trimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid 
• 110410-91-8 (2S,3S,4R)-3-Hydroxymethyl-6,7-dimethoxy-4-(3,4,5-trimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid 
• 1178-12-7 (3aS,9S,9aS)-6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3,3a,9,9a-tetrahydro-naphtho[2,3-c]furan-1,4-dione 
• 1178-09-2 (+/-)-4-episikkimotoxin 
• 1178-09-2 (+/-)-sikkimotoxin 

Relevant academic research and scientific papers

THE TOTAL SYNTHESIS OF (+/-)-SIKKIMOTOXIN VIA THE BENZO-PETERSON REACTION

The total synthesis of a lignan lactone sikkimotoxin (1) in racemic forms has been completed by employing the Benzo-Peterson reaction as key step.

A FACILE SYNTHESIS OF THE SUBSTITUTED TETRAHYDRONAPHTHALENES BY THE BENZO-PETERSON REACTION

Thermal treatment of the o-hydroxymethylbenzylsilanes with an excess maleic anhydride or 2,3-dichloromaleic anhydride afforded the corresponding substituted tetrahydronaphthalenes stereoselectively in satisfactory yields presumably via the o-quinodimethane intermediates generated by the benzo-Peterson reaction.