1043-08-9

Basic information

• Product Name: 5,8-Dihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one
• Synonyms: 5,8-Dihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one;Osajaxanthone
• CAS NO: 1043-08-9
• Molecular Formula: C18H14 O5
• Molecular Weight: 0
• Mol File: 1043-08-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,8-Dihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,8-Dihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one(1043-08-9)
• EPA Substance Registry System: 5,8-Dihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one(1043-08-9)

Safety Data

• Hazardous Substances Data: 1043-08-9(Hazardous Substances Data)

Upstream product

• 106296-25-7 methyl 2,5-bis(phenylmethoxy)benzoate 
• 2150-46-1 Methyl 2,5-dihydroxybenzoate 
• 39838-86-3 7-hydroxy-1,3-dimethoxy-9H-xanthen-9-one 
• 900501-59-9 (2,5-dibenzyloxyphenyl)(2,4,6-trimethoxyphenyl)methanone 
• 900501-63-5 (2,5-dihydroxyphenyl)(2,4,6-trimethoxyphenyl)methanone 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 529-49-7 gentitein 

Relevant articles and documents

Facile synthesis of 1,3,7-trihydroxyxanthone and its regioselective coupling reactions with prenal: Simple and efficient access to osajaxanthone and nigrolineaxanthone F

A facile five-step synthesis of naturally occurring 1,3,7- trihydroxyxanthone has been described starting from 1,3,5-trimethoxybenzene via NBS-induced nuclear bromination, lithiation followed by an in situ benzoylation with methyl 2,5-dibenzyloxybenzoate, selective deprotection of the two benzyl groups, base-catalyzed intramolecular cyclization, and demethylations pathway with 62% overall yield. The regioselective coupling reactions of 1,3,7-trihydroxyxanthone with prenal in the presence of calcium hydroxide at room temperature and under thermal conditions at 140-150 °C have been demonstrated to exclusively obtain the natural products osajaxanthone in 15% yield and nigrolineaxanthone F in 98% yield, respectively.