104315-85-7Relevant academic research and scientific papers
Metal-free and light-promoted radical iodotrifluoromethylation of alkenes with Togni reagent as the source of CF3 and iodine
Beniazza, Redouane,Douarre, Maxime,Lastécouères, Dominique,Vincent, Jean-Marc
, p. 3547 - 3550 (2017)
A light-promoted methodology for the iodotrifluoromethylation of alkenes was developed. For the first time a Togni reagent was exploited as the source of both the CF3 group and iodine atom. Preliminary mechanistic studies suggest that both CF3I and 2-iodobenzoic acid are direct sources of the iodine atom that is transferred to the products.
A general and green fluoroalkylation reaction promoted: Via noncovalent interactions between acetone and fluoroalkyl iodides
Mao, Ting,Ma, Ming-Jian,Zhao, Liang,Xue, De-Pu,Yu, Yanbo,Gu, Jiwei,He, Chun-Yang
, p. 1815 - 1818 (2020)
The first example of visible light promoted fluoroalkylation reactions initiated via noncovalent interactions between acetone and fluoroalkyl iodides is presented. The reaction system features synthetic simplicity, mild reaction conditions without any photoredox catalyst, and high functional group tolerance. A wide range of substrate scopes such as alkenes, alkynes and (hetero)arenes were all compatible with the reaction system.
Visible-Light-Mediated Iodoperfluoroalkylation of Alkenes in Flow and Its Application to the Synthesis of a Key Fulvestrant Intermediate
Rosso, Cristian,Williams, Jason D.,Filippini, Giacomo,Prato, Maurizio,Kappe, C. Oliver
supporting information, p. 5341 - 5345 (2019/07/03)
Two efficient continuous flow iodoperfluoroalkylation methods are described: using 0.05 mol % perylene diimide (PDI) photocatalyst under 450 nm irradiation or substoichiometric triethylamine under 405 nm irradiation. These methods enable dramatically elevated productivity versus batch processes. The triethylamine-mediated method is explored mechanistically and in substrate scope. The gram-scale synthesis of an active pharmaceutical ingredient side chain is also reported in flow, via a photochemical iodoperfluoroalkylation followed by hydrogenolysis.
PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
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Paragraph 0668; 0669; 0670, (2016/05/02)
This document discloses molecules having the following formula (“Formula One”): and processes related thereto.
PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
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Paragraph 0671-0672, (2013/11/06)
This document discloses molecules having the following formula (“Formula One”): and processes related thereto.
Sodium dithionite initiated addition of CF2Br2, CF3I and (CF3)2CFI to allylaromatics. Synthesis and the reactivity of 4-aryl-1,1-difluorodienes and 4-aryl-1,1-bis(trifluoromethyl)dienes
Ignatowska, Jolanta,Dmowski, Wojciech
, p. 997 - 1006 (2008/02/10)
Sodium dithionite initiated addition of CF2Br2, CF3I and (CF3)2CFI to the terminal double bond of allylbenzenes and of (CF3)2CFI to allylpyridines in a MeCN/H2O system
ORGANOALUMINUM-INDUCED ADDITION OF POLYHALOMETHANE TO OLEFINS
Maruoka, Keiji,Sano, Hiromi,Fukutani, Yoshimi,Yamamoto, Hisashi
, p. 1689 - 1692 (2007/10/02)
A mild procedure for the trimethylaluminum-induced addition of polyhalomethane to olefins has been described.
