104317-84-2 Usage
Uses
Used in Transplantation:
Gusperimus is used as an immunosuppressive agent for the prevention of accelerated and acute rejection reactions after kidney transplants. It helps prolong the survival of transplant allografts and induces transplant tolerance.
Used in Autoimmune Diseases:
Gusperimus is used as a treatment for autoimmune diseases such as multiple sclerosis, systemic lupus, diabetes mellitus, rheumatoid arthritis, and nephrosis. It suppresses autoimmune responses and helps manage the symptoms of these conditions.
Used in Graft Rejection:
Gusperimus is used in combination therapy with other agents, such as cyclosporine A, for the prevention of transplant rejection and to induce long-term tolerance. It exhibits exceptional activity in combination therapy and helps improve the success rate of transplants.
Used in Cancer Treatment:
Gusperimus is in clinical trials for its potential use as an anticancer agent. It inhibits the differentiation and proliferation of effector cells, including cytotoxic T cells and antibody-producing B cells, which may help in the treatment of various types of cancer.
Originator
Nippon Kayaku (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 104317-84-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,3,1 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 104317-84:
(8*1)+(7*0)+(6*4)+(5*3)+(4*1)+(3*7)+(2*8)+(1*4)=92
92 % 10 = 2
So 104317-84-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H37N7O3/c18-9-7-11-21-10-5-6-12-22-15(26)16(27)24-14(25)8-3-1-2-4-13-23-17(19)20/h16,21,27H,1-13,18H2,(H,22,26)(H,24,25)(H4,19,20,23)
