10432-55-0Relevant academic research and scientific papers
Synthesis of dimethyl glutarate from cyclobutanone and dimethyl carbonate over solid base catalysts
Zhi, Chen,Dudu, Wu
experimental part, p. 1834 - 1838 (2012/07/31)
A facile route for the synthesis of dimethyl glutarate (DMG) from cyclobutanone and dimethyl carbonate (DMC) in the presence of solid base catalysts has been developed. It was found that the intermediate carbomethoxycyclobutanone (CMCB) was produced from cyclobutanone with DMC in the first step, and then CMCB was further converted to DMG by reacting with a methoxide group. The role of the basic catalysts can be mainly ascribed to the activation of cyclobutanone via the abstraction of a proton in the α-position by base sites, and solid bases with moderate strength, such as MgO, favor the formation of DMG.
Reactions of alkali metal anions. XV. Reaction of ketones with alkali metal anions
Jedlinski,Misioiek,Giowkowski,Janeczek,Wolinska
, p. 3547 - 3558 (2007/10/02)
The potassium anions were found to react with ketones to39 yield both alcoholates and enolates. On the basis of the ESR and K NMR measurements the mechanism of this reaction is proposed. According to the proposed mechanism in the first step a ketyl radical is formed which after disproportionation yields an enolate and an alcoholate but only in the case of ketones having hydrogen atom in α-position in respect to carbonyl group.
