104325-55-5

Basic information

• Product Name: [3-(QUINOLIN-2-YLMETHOXY)-PHENYL]-ACETIC ACID
• Synonyms: [3-(QUINOLIN-2-YLMETHOXY)-PHENYL]-ACETIC ACID;3-(2-quinolinylmethoxy)benzeneacetic acid;Wy-46016
• CAS NO: 104325-55-5
• Molecular Formula: C₁₈H₁₅NO₃
• Molecular Weight: 293.3166
• Mol File: 104325-55-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 500°Cat760mmHg
• Flash Point: 256.2°C
• Appearance: /
• Density: 1.281g/cm³
• Vapor Pressure: 8.12E-11mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: [3-(QUINOLIN-2-YLMETHOXY)-PHENYL]-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(QUINOLIN-2-YLMETHOXY)-PHENYL]-ACETIC ACID(104325-55-5)
• EPA Substance Registry System: [3-(QUINOLIN-2-YLMETHOXY)-PHENYL]-ACETIC ACID(104325-55-5)

Safety Data

• Hazardous Substances Data: 104325-55-5(Hazardous Substances Data)

Usage

General Description

[3-(quinolin-2-ylmethoxy)-phenyl]-acetic acid is a chemical compound that consists of a phenyl ring connected to an acetic acid moiety and a quinoline ring attached to the phenyl ring through a methoxy group. It is a synthetic compound, and its chemical structure includes a quinoline group, which is a heterocyclic aromatic ring system, and an acetic acid group. [3-(QUINOLIN-2-YLMETHOXY)-PHENYL]-ACETIC ACID may have potential pharmaceutical applications due to its structural similarity to known bioactive molecules. Its chemical properties and potential biological activities make it an interesting target for further research and development in the field of medicinal chemistry.

InChI:InChI=1/C18H15NO3/c20-18(21)11-13-4-3-6-16(10-13)22-12-15-9-8-14-5-1-2-7-17(14)19-15/h1-10H,11-12H2,(H,20,21)

Upstream product

• 4377-41-7 2-Chloromethylquinoline 
• 102-29-4 Resorcinol monoacetate 
• 104325-56-6 methyl 3-(2-quinolinylmethoxy)benzeneacetate 
• 42058-59-3 3-hydroxy-benzeneacetic acid, methyl ester 

Downstream Products

• 123723-96-6 N-Methoxy-N-methyl-2-[3-(quinolin-2-ylmethoxy)-phenyl]-acetamide 
• 118308-97-7 3-[(2-quinolinyl)methoxy]benzeneaceto hydroxamic acid 
• 118308-94-4 Wy 48,422 
• 118308-96-6 N-Benzyloxy-2-[3-(quinolin-2-ylmethoxy)-phenyl]-acetamide 
• 119514-96-4 N-[(4-Methylphenyl)sulfonyl]-3-(2-quinolinylmethoxy)benzeneethanamide 

Relevant articles and documents

CYANOMETHYLPYRIDINE DERIVATIVES

The present invention relates to new cyanomethylpyridine dervatives of formula I wherein Y represents N or CH;R1 represents hydrogen, fluoro, chloro, difluoro or dichloro; R2 represents hydrogen or C1-4alkyl;n is 0 or 1; p is 0 or 1; A represents a covalent bond or a group of formula -CONHC-H(Ar)-, -NHCH(Ar)-, -S02NHCH(Ar)-,NHCONHCH(Ar) or OCONHCH(Ar),and when p is 1,A can also represent CH(Ar)NH; and AT represents phenyl or phenyl substituted with halogen,C M alkyl, C1-4 alkoxy or trifluoromethyl. These compounds are PAF antagonist and/or 5-lipoxygenase inhibitors.

Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity

Compounds of the formula: and salts thereof, wherein Ar1 is a nitrogen, sulfur or oxygen heterocyclic ring; Ar is a phenyl ring or a nitrogen, oxygen or sulfur heterocyclic ring; Ar and Ar1 may be fully substituted or less than fully substituted with H, CH3, lower alkyl, aryl, aralkyl, halo, hydroxy, lower alkoxy, CF3, carboxy, alkylcarboxy, arylcarboxy, alkylcarbalkoxy, alkanoyl, formyl, oxo, nitrilo, amino, aminoalkyl, alkylamine, carboxamide, aryloxy, nitro, sulfonyl, sulfonamide, thio, alkylthio, hydroxyalkyl or oxyalkylcarbalkoxy; X= STR1 of up to 2 carbon atoms in the principal chain and up to a total of 4 carbon atoms, STR2 Z is an alkylene chain containing up to 10 carbon atoms in the principal chain and a total of up to 12 carbon atoms and from 0 to 2 double bonds and the said alkylene chain may be attached to Ar through an oxygen, sulfur or amino nitrogen atom, and when n'=2, one of the R substituents may be halogen on an omega carbon of the alkylene chain Z; when n'=1, R is a substituent attached to one of the carbon atoms of Z selected from the group consisting of =O, OR3, SR3, N(R2)2 and R1, --COR4 and when n'=2 one R is previously defined and the additional R is a substituent attached to one of the carbon atoms of Z selected from the group consisting of =O, OR3, SR3, N(R2)2, --COR4, lactone and halo; R1 is H or CH3 ; R2 is H, lower alkyl, aryl or aralkyl; R3 is H, lower alkyl, lower alkanoyl, aryl, aralkyl or substituted aryl in which the substituent is halo, lower alkyl or lower alkoxy; R4 is OR2 or N(R2)2 ; n=0 or 1; n'=1 to 7; and n"=0, 1 or 2.