104333-72-4Relevant academic research and scientific papers
Synthesis of 3α-alkoxy-4β-substituted-2-azetidinones from L(+)-tartaric acid
Barton, Derek H. R.,Cleophax, Jeanine,Gateau-Olesker, Alice,Gero, Stephan D.,Tachdjian, Catherine
, p. 8381 - 8396 (2007/10/02)
Tartaric acid, regioselective saponification, Pig Liver Esterase, 3-methoxy-2-azetidinone, N-Hydroxy-2-thiopyridone, radical decarboxylation. The synthesis of 3α-alkoxy-4β-azetidinones from L(+) tartaric acid is described. Regioselective saponification and methylation along with a stereo selective radical decarboxylative alkylation are key steps leading to optically pure trans-β-lactams.
