104339-66-4

Basic information

• Product Name: HISTATIN-5
• Synonyms: DSHAKRHHGYKRKFHEKHHSHRGY;H-ASP-SER-HIS-ALA-LYS-ARG-HIS-HIS-GLY-TYR-LYS-ARG-LYS-PHE-HIS-GLU-LYS-HIS-HIS-SER-HIS-ARG-GLY-TYR-OH;HISTATIN-5;HISTATIN 5 (HUMAN);ASP-SER-HIS-ALA-LYS-ARG-HIS-HIS-GLY-TYR-LYS-ARG-LYS-PHE-HIS-GLU-LYS-HIS-HIS-SER-HIS-ARG-GLY-TYR;Histatin 5【human parotid saliva】;L-Asp-L-Ser-L-His-L-Ala-L-Lys-L-Arg-L-His-L-His-Gly-L-Tyr-L-Lys-L-Arg-L-Lys-L-Phe-L-His-L-Glu-L-Lys-L-His-L-His-L-Ser-L-His-L-Arg-Gly-L-Tyr-OH
• CAS NO: 104339-66-4
• Molecular Formula: C133H195N51O33
• Molecular Weight: 3036.29
• Product Categories: Peptide
• Mol File: 104339-66-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: HISTATIN-5(CAS DataBase Reference)
• NIST Chemistry Reference: HISTATIN-5(104339-66-4)
• EPA Substance Registry System: HISTATIN-5(104339-66-4)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 104339-66-4(Hazardous Substances Data)

Usage

General Description

HISTATIN-5 is a naturally occurring antimicrobial peptide found in human saliva that plays a crucial role in protecting the oral cavity from microbial infection. This peptide has potent antifungal properties and is known for its ability to inhibit the growth of the fungus Candida albicans, which can cause oral infections such as oral thrush. HISTATIN-5 works by disrupting the cell membrane of the fungus, leading to its death. In addition to its antifungal activity, HISTATIN-5 also possesses antibacterial properties and helps maintain the balance of the oral microbiota. Studies have shown that HISTATIN-5 may have potential therapeutic applications in the treatment of oral candidiasis and other oral infections.

InChI:InChI=1/C133H195N51O33/c1-71(164-120(206)96(46-76-54-146-65-158-76)181-128(214)103(62-185)183-110(196)84(138)52-108(193)194)109(195)167-86(18-5-9-35-134)113(199)172-91(24-15-41-154-133(143)144)118(204)178-99(49-79-57-149-68-161-79)125(211)176-95(45-75-53-145-64-157-75)112(198)156-60-105(189)165-93(43-73-25-29-82(187)30-26-73)121(207)173-87(19-6-10-36-135)114(200)171-90(23-14-40-153-132(141)142)115(201)169-88(20-7-11-37-136)116(202)175-94(42-72-16-3-2-4-17-72)122(208)179-97(47-77-55-147-66-159-77)124(210)174-92(33-34-107(191)192)119(205)170-89(21-8-12-38-137)117(203)177-100(50-80-58-150-69-162-80)126(212)180-101(51-81-59-151-70-163-81)127(213)184-104(63-186)129(215)182-98(48-78-56-148-67-160-78)123(209)168-85(22-13-39-152-131(139)140)111(197)155-61-106(190)166-102(130(216)217)44-74-27-31-83(188)32-28-74/h2-4,16-17,25-32,53-59,64-71,84-104,185-188H,5-15,18-24,33-52,60-63,134-138H2,1H3,(H,145,157)(H,146,158)(H,147,159)(H,148,160)(H,149,161)(H,150,162)(H,151,163)(H,155,197)(H,156,198)(H,164,206)(H,165,189)(H,166,

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