104340-34-3

Basic information

• Product Name: Benzenamine, 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-
• CAS NO: 104340-34-3
• Molecular Formula: C14H13N3OS
• Molecular Weight: 271.343
• Mol File: 104340-34-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-(104340-34-3)
• EPA Substance Registry System: Benzenamine, 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-(104340-34-3)

Safety Data

• Hazardous Substances Data: 104340-34-3(Hazardous Substances Data)

Upstream product

• 75-18-3 dimethylsulfide 
• 104340-33-2 2-<(1H-benzimidazol-2-ylthio)methyl>aniline 
• 111881-64-2 (2-hydroxymethyl-phenyl)-carbamic acid benzyl ester 
• 5344-90-1 2-Aminobenzyl alcohol 
• 134469-07-1 Benzimidazol-2-thiol 
• 108499-76-9 2-<2-((benzyloxycarbonyl)aminobenzyl)thio>-1H-benzimidazole 

Downstream Products

• 5344-90-1 2-Aminobenzyl alcohol 
• 134469-07-1 Benzimidazol-2-thiol 

Relevant articles and documents

METHOD OF USING (H+/K+)ATPASE INHIBITORS AS ANTIVIRAL AGENTS

A class of compounds which are (H+/K+) ATPase inhibitors can be used for the treatment of viral infections. Compounds of particular interest are defined by Formula III: wherein D is N or CH; wherein R7 is one or more radicals selected from hydrido, alkoxy, amino, cyano, nitro, hydroxyl, alkyl, halo, haloalkyl, carboxyl, alkanoyl, nitro, amino, alkylamino, aminocarbonyl , aminosulfonyl , alkylaminocarbonyl, alkylcarbonylamino, alkoxycarbonyl, alkylaminosulfonyl, alkylsulfonylamino, alkylthio, alkyl-sulfinyl and alkylsulfonyl; wherein R8 is selected from hydrido, alkyl and cycloalkyl; wherein R9 is one or more radicals selected from hydrido, alkoxy, amino, alkyl, halo, cyano, nitro, hydroxyl, haloalkyl, nitro, carboxyl, alkanoyl, amino, alkylamino, dialkylamino, aminocarbonyl , alkylaminocarbonyl, alkylcarbonylamino, aminosulfonyl, alkylaminosulfonyl, alkylsulfonylamino, alkoxycarbonyl, alkylthio, alkylsulfinyl and alkylsulfonyl; and wherein R10 and R11 are independently selected from hydrido, alkyl, aryl, alkylcarbonyl and arylcarbonyl wherein the aryl ring may be further substituted with one or more radicals selected from alkyl, halo, hydrazidylcarbonyl, aminocarbonyl and alkoxy; or wherein R10 and R11 together with the nitrogen atom form a heterocyclic ring

Stabilized benzimidazole derivative and composition

A stabilized physiologically active benzimidazole derivative having the formula (I): STR1 wherein R1 is hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a fluoroalkyl group having 1 to 6 carbon atoms, a cycloalkyl group, phenyl group or an aralkyl group, R2 is hydrogen atom or a lower alkyl group, or R1 and R2 together with the adjacent nitrogen atom form a ring, and each of R3a, R3b, R4a, R4b and R4c independently is hydrogen atom, a halogen atom, a fluoroalkyl group having 1 to 6 carbon atoms, a lower alkyl group, a lower alkoxy group, a lower alkoxycarbonyl group or an amino group. The stabilized benzimidazole derivative is in amorphous form or present in contact with a basic material.

Use of benzylsulfinylbenzimidazoles as cytoprotective agents for the gastrointestinal tract

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