1043446-67-8Relevant academic research and scientific papers
Chiral amino alcohols derived from natural amino acids as chiral solvating agents for carboxylic acids
Wang, Wenge,Shen, Xiumin,Ma, Fengnian,Li, Zijing,Zhang, Cong
, p. 1193 - 1199 (2008)
Several chiral amino alcohols have been synthesized conveniently and effectively. 1H NMR was utilized to investigate their enantiodiscriminating abilities. Chiral amino alcohols 2 and 4 were discovered as efficient CSAs for the determination of the enantiomeric compositions of chiral carboxylic acids. In particular, for the Ts-derivatives of amino acids studied herein, 4 could be used for the assignment of the absolute configurations of the Ts-derivatives of amino acids with a neutral side chain through the chemical shift non-equivalences of their NH (Ts) protons with certain confidence.
