1043452-74-9

Basic information

• Product Name: (8R,9S)-8-chloro-9-hydroxy-8,9-deoxyaspyrone
• CAS NO: 1043452-74-9
• Molecular Weight: 220.653
• Mol File: 1043452-74-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (8R,9S)-8-chloro-9-hydroxy-8,9-deoxyaspyrone(CAS DataBase Reference)
• NIST Chemistry Reference: (8R,9S)-8-chloro-9-hydroxy-8,9-deoxyaspyrone(1043452-74-9)
• EPA Substance Registry System: (8R,9S)-8-chloro-9-hydroxy-8,9-deoxyaspyrone(1043452-74-9)

Safety Data

• Hazardous Substances Data: 1043452-74-9(Hazardous Substances Data)

Upstream product

• 17398-00-4 aspyrone 

Relevant articles and documents

Chlorohydroaspyrones A and B, antibacterial aspyrone derivatives from the marine-derived fungus Exophiala sp.

Chlorohydroaspyrones A (1) and B (2), antibacterial aspyrone derivatives, and the previously described aspyrone (3), asperlactone (4), and penicillic acid (5) have been isolated from the broth of a marine isolate of the fungus Exophiala. The structure and absolute stereochemistry of the compounds were determined on the basis of the physicochemical data analysis and chemical reactions. Compounds 1 and 2 exhibited a mild antibacterial activity against Staphylococcus aureus, methicillin-resistant S. aureus, and multidrug-resistant S. aureus. The MIC values of each strain are as follows: compound 1 showed 62.5 μg/mL for S. aureus and 125 μg/mL for methicillin-resistant S. aureus and multidrug-resistant S. aureus, and compound 2, 62.5 μg/mL for S. aureus and methicillin-resistant S. aureus and 125 μg/mL for multidrug-resistant S. aureus.