1043469-14-2Relevant articles and documents
Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method via a triamino mitosene
Champeil, Elise,Paz, Manuel M.,Ladwa, Sweta,Clement, Cristina C.,Zatorski, Andrzej,Tomasz, Maria
experimental part, p. 9556 - 9565 (2009/02/02)
The cancer chemotherapeutic agent mitomycin C (MC) alkylates and cross-links DNA monofunctionally and bifunctionally in vivo and in vitro, forming six major MC-deoxyguanosine adducts of known structures. The synthesis of one of the monoadducts (8) by the