1043508-62-8

Basic information

• Product Name: C₁₆H₂₄P₂
• CAS NO: 1043508-62-8
• Molecular Weight: 278.314
• Mol File: 1043508-62-8.mol

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₄P₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₄P₂(1043508-62-8)
• EPA Substance Registry System: C₁₆H₂₄P₂(1043508-62-8)

Safety Data

• Hazardous Substances Data: 1043508-62-8(Hazardous Substances Data)

Upstream product

• 5732-44-5 1,3,2-dioxathiepane 2,2-dioxide 
• 80510-04-9 1,2-bis(phosphino)benzene 
• 220224-82-8 (4S,7S)-4,7-dimethyl-1,3,2-dioxathiepane 2,2-dioxide 

Relevant articles and documents

Probing the importance of the hemilabile site of bis(phosphine) monoxide ligands in the copper-catalyzed addition of diethylzinc to N-phosphinoylimines: Discovery of new effective chiral ligands

(Chemical Equation Presented) The hemilabile ligand Me-DuPHOS(O) 2 has proven to be a successful ligand for the copper-catalyzed addition of diethylzinc to N-phosphinoylimines. The corresponding α-chiral amines were obtained in high yields (80-98%) and enantiomeric ratios (19.0:1 to 99.0:1 er). Furthermore, this Cu?2 catalytic system has been shown to be effective in the addition of diethylzinc to nitroalkenes and in the reduction of β,β-disubstituted vinyl phenyl sulfones. This paper describes a general structure/selectivity study in which the three ligand subunits (chiral phospholane-linker-labile coordinating group (Z)) are systematically modified and tested in the copper-catalyzed addition of diethylzinc to the N-phosphinoylimine 1 derived from benzaldehyde. This study led to the discovery of a new class of effective chiral ligands that combine a chiral phospholane unit and an achiral phosphine oxide.