104372-02-3Relevant academic research and scientific papers
Asymmetric synthesis of (+)- and (-)-latifine
Couture, Axel,Deniau, Eric,Grandclaudon, Pierre,Lebrun, Stephane
, p. 1309 - 1316 (2007/10/03)
A concise and novel synthesis of isoquinoline alkaloids (S)-latifine and of its antipode is reported. The key step relies on the stereoselective reduction of an appropriately substituted diarylenamine equipped with a chiral auxiliary followed by Pictet-Sp
Total Synthesis of (+/-)- and (+)-Latifine
Takano, Seicchi,Akiyama, Masashi,Ogasawara, Kunio
, p. 2447 - 2454 (2007/10/02)
Racemic latifine (+)-(1), a new representative of the rare phenolic Amaryllidaceae alkaloids, has been synthesized by employing the Claisen rearrangement of 4-benzyloxycinnamyl 2-methoxyphenyl ether (11) as a key step.Based on the racemic synthesis, (R)-(
