104385-58-2

Upstream product

• 104385-57-1 (1S,2R)-1-Dimethoxymethyl-2-((E)-styryl)-8-oxa-bicyclo[3.2.1]oct-6-en-3-one 
• 98-01-1 furfural 
• 54985-34-1 trans-1-phenyl-1-penten-3-ol 
• 16330-23-7 1-phenyl-1-pentyn-4-ol 
• 536-74-3 phenylacetylene 
• 104385-55-9 3-bromo-5-phenylpent-4(E)-ene-2-one 
• 42762-56-1 (E)-5-phenylpent-4-en-2-one 
• 1453-62-9 2-furaldehyde dimethyl acetal 

Downstream Products

• 104385-60-6 (1S,3R,4S,5S,7S,8S)-3-dimethoxymethyl-8-iodo-4-<(E)-1'-styryl>-2,6-dioxatricyclo<3.3.1.0^3,7>nonane 
• 104385-59-3 (1S,3S,5S,7R,8S,9S)-1-dimethoxymethyl-8-iodo-9-<(E)-1'-styryl>-2,6-dioxatricyclo<3.3.1.0^3,7>nonane 
• 104385-62-8 (1S,3S,4S,5S)-3-Dimethoxymethyl-4-((E)-styryl)-2,6-dioxa-tricyclo[3.3.1.0^3,7]nonane 
• 104385-60-6 (1S,3S,4S,5S)-3-Dimethoxymethyl-8-iodo-4-((E)-styryl)-2,6-dioxa-tricyclo[3.3.1.0^3,7]nonane 
• 104385-59-3 (1R,3S,5S,9S)-1-Dimethoxymethyl-8-iodo-9-((E)-styryl)-2,6-dioxa-tricyclo[3.3.1.0^3,7]nonane 

Relevant academic research and scientific papers

Thromboxane A2 Analogues from 8-Oxabicyclooct-6-en-3-ones

We describe approaches to thromboxane A2 analogues (3), (4), and (32) which contain 2,6-dioxabicyclooctane and 2,6-dioxatricyclo3,7>nonane ring system.Both were derived from 2-substituted 8-oxabicyclooct-6-en-3-

OXYALLYLS IN SYNTHESIS: PREPARATION OF TRICYCLIC THROMBOXANE A2 ANALOGUES

We describe the formation of 1-(dimethoxymethyl)-2-(2-phenylethenyl)-8-oxabicyclooct-6-en-3-ol (4) using oxyallyl methodology, and conversion of this into two 2,6-dioxatricyclo3,7> nonanes (9) and (10) via iodoetherification and reduction.These compounds were then elaborated into the novel thromboxane analogues (11) and (12).