1043875-01-9Relevant academic research and scientific papers
Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization
Alvarez, Concepcion,Alvarez, Raquel,Corchete, Purificacion,Lopez, Jose Luis,Perez-Melero, Concepcion,Pelaez, Rafael,Medarde, Manuel
, p. 5952 - 5961 (2008/12/21)
We describe the synthesis and biological evaluation of a series of diarylmethyloxime and diarylmethylhydrazone analogues that contain an indole ring and different modifications on the nitrogen of the bridge. Several compounds showed potent tubulin polymer
