1043896-80-5Relevant articles and documents
Novel quinolinonyl diketo acid derivatives as HIV-1 integrase inhibitors: Design, synthesis, and biological activities
Di Santo, Roberto,Costi, Roberta,Roux, Alessandra,Miele, Gaetano,Crucitti, Giuliana Cuzzucoli,Iacovo, Alberto,Rosi, Federica,Lavecchia, Antonio,Marinelli, Luciana,Di Giovanni, Carmen,Novellino, Ettore,Palmisano, Lucia,Andreotti, Mauro,Amici, Roberta,Galluzzo, Clementina Maria,Nencioni, Lucia,Palamara, Anna Teresa,Pommier, Yves,Marchand, Christophe
, p. 4744 - 4750 (2008)
Novel quinolinonyl diketo acids were designed to obtain integrase (IN) inhibitors selectively active against the strand transfer (ST) step of the HIV integration process. Those new compounds are characterized by a single aryl diketo acid (DKA) chain in co