1043931-99-2Relevant articles and documents
Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation
Fortin, Jessica S.,Cote, Marie-France,Lacroix, Jacques,Patenaude, Alexandre,Petitclerc, Eric,C.-Gaudreault, Rene
supporting information; experimental part, p. 3526 - 3531 (2009/04/11)
1-(2-Chloroethyl)-3-(4-cyclohexylphenyl)urea (cHCEU) has been shown to abrogate the presence of thioredoxin-1 into the nucleus through its selective covalent alkylation. In the present letter we have evaluated the structure-activity relationships of the s