104395-04-2Relevant academic research and scientific papers
Stereochemical Studies on Hemiorthothiol and Hemiorthothiolate Tetrahedral Intermediates
Khouri, Farid F.,Kaloustian, Moses K.
, p. 6683 - 6695 (1986)
This study deals with hemiorthothiol-RC(OR')2SH-tetrahedral intermediates including (a) two acyclic ones of type , (b) two types of monocyclics and , and (c) four bicyclic systems , , , and .The breakdown of (R = Ph, R' = Et) led to thiono esters 34 and 35; that of (R = Me, Ph) resulted in hydroxy thiono esters 36-39, whereas the cleavage of (R =Me, Et) yielded thionolactones 49-53 and hydroxy thiono esters 55-58.The study of rigid bicyclic intermediates - helped uncover the role of stereoelectronic effects in the breakdown of hemiorthothiol tetrahedral intermediates.Finally, a family of isolable hemiorthothiolate tetrahedral intermediates-RC(OR')2S-+Na-viz. ->--> (monocyclic) and -> (bicyclic) is reported.
