10441-45-9 Usage
Synthesis Reference(s)
Journal of the American Chemical Society, 82, p. 1450, 1960 DOI: 10.1021/ja01491a043
Purification Methods
Crystallise the acid from EtOH/water (1:9, v/v, activated charcoal), H2O (m 157o) or xylene (m 147o). Dry it under vacuum, over silica gel, in the dark. Store it in the dark at -20o [Gafni et al. J Phys Chem 80 898 1976]. It forms a cyclic lactone (m 107o) readily. [Beilstein 10 II 218, 10 III 1102, 10 IV 1201.]
Check Digit Verification of cas no
The CAS Registry Mumber 10441-45-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,4 and 1 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10441-45:
(7*1)+(6*0)+(5*4)+(4*4)+(3*1)+(2*4)+(1*5)=59
59 % 10 = 9
So 10441-45-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H10O3/c13-11-6-5-8-3-1-2-4-9(8)10(11)7-12(14)15/h1-6,13H,7H2,(H,14,15)
10441-45-9Relevant articles and documents
Palladium-Catalyzed 2-(Neopentylsulfinyl)aniline Directed C–H Acetoxylation and Alkenylation of Arylacetamides
Barysevich, Maryia V.,Laktsevich-Iskryk, Marharyta V.,Krech, Anastasiya V.,Zhabinskii, Vladimir N.,Khripach, Vladimir A.,Hurski, Alaksiej L.
supporting information, p. 937 - 943 (2020/02/25)
The 2-(neopentylsulfinyl)aniline directing group that promotes rapid palladium-catalyzed C–H acetoxylation and alkenylation of arylacetamides has been developed. The acetoxylation reaches completion within only 40 min at 100 °C and leads to the bis-functionalized products. Alternatively, the reaction can be carried out at room temperature, which is beneficial for sensitive substrates. For the alkenylation, we have developed a protocol in which easily available 1-substituted cyclopropanols were employed as equivalents of vinyl ketones.
