1044148-61-9Relevant academic research and scientific papers
Palladium/sulfoxide-phosphine-catalyzed highly enantioselective allylic etherification and amination
Feng, Bin,Cheng, Hong-Gang,Chen, Jia-Rong,Deng, Qiao-Hui,Lu, Liang-Qiu,Xiao, Wen-Jing
supporting information, p. 9550 - 9553 (2014/08/18)
The Pd/sulfoxide-phosphine-catalyzed highly enantioselective allylic etherification and amination with a wide range of O- and N-nucleophiles have been developed (up to 97% yield, 98.5% ee). The products can also be conveniently transformed into biologically active chiral heterocycles. This journal is the Partner Organisations 2014.
Stereospecific ring expansion of chiral vinyl aziridines
Brichacek, Matthew,Navarro Villalobos, Mauricio,Plichta, Alexandra,Njardarson, Jon T.
, p. 1110 - 1113 (2011/04/25)
In this report, it is demonstrated that chiral vinyl aziridines can be stereospecifically ring expanded. This synthetic approach allows controlled access to chiral 2,5-cis-or 2,5-trans-3-pyrroline products from starting materials with the appropriate aziridine geometry. Twenty three ring expansion examples, most of which feature a stereospecific cyclization, are presented.(Figure Presented)
A novel access to tetrahydro-β-carbolines via one-pot hydroformylation/fischer indole synthesis: Rearrangement of 3,3- spiroindoleninium cations
Bondzic, Bojan P.,Eilbracht, Peter
supporting information; experimental part, p. 3433 - 3436 (2009/05/07)
(Chemical Equation Presented) The two component one-pot hydroformylation/Fischer indole synthesis sequence of 2,5 dihydropyrroles and phenyl hydrazines allows a facile and convenient access to tetrahydro-β- carbolines in moderate to good yields.
