104416-44-6

Basic information

• Product Name: 1-Propanone, 3-hydroxy-1-(2-hydroxyphenyl)-2-methyl-
• CAS NO: 104416-44-6
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol File: 104416-44-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 3-hydroxy-1-(2-hydroxyphenyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 3-hydroxy-1-(2-hydroxyphenyl)-2-methyl-(104416-44-6)
• EPA Substance Registry System: 1-Propanone, 3-hydroxy-1-(2-hydroxyphenyl)-2-methyl-(104416-44-6)

Safety Data

• Hazardous Substances Data: 104416-44-6(Hazardous Substances Data)

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 107-18-6 allyl alcohol 
• 50-00-0 formaldehyd 
• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 

Downstream Products

• 16982-86-8 3-methyl-chroman-4-one 
• 104416-46-8 3-Hydroxy-2-hydroxymethyl-2-methyl-1-(o-hydroxyphenyl)-1-propanone 

Relevant articles and documents

Double-Chelation-Assisted Rh-Catalyzed Intermolecular Hydroacylation between Salicylaldehydes and 1,4-Penta- or 1,5-Hexadienes

Intermolecular hydroacylation between salicylaldehydes 1, 26-40 and 1,4-penta- or 1,5-hexadienes 4-13 by Rh-catalyst proceeded under mild reaction conditions to give a mixture of iso- and normal-hydroacylated products 14-25, 41-55, and 57-60. In the hydroacylation reaction, chelation of both salicylaldehyde and diene to the Rh-complex plays a crucial role. The ratio of iso- and normal-hydroacylated products could be regulated by the addition of salicylic acid or amines. The effects of various Rh-complexes, solvents, and additives were examined, and the plausible mechanisms of the catalytic cycle were proposed on the basis of the deuterium-labeling salicylaldehyde experiments.