10442-83-8

Basic information

• Product Name: HC Yellow 13
• Synonyms: HC YELLOW 13;HC YELLOW NO. 13;HCYELLOW;2-[[2-Nitro-4-(trifluoromethyl)phenyl]amino]ethanol;4-(2-Hydroxyethylamino)-3-nitrobenzotrifluoride;2-{[2-nitro-4-(trifluoromethyl)phenyl]amino}ethanol(SALTDATA: FREE);N-(2-Hydroxyethyl)-2-nitro-5-(trifluoroMethyl)aniline;2-[2-nitro-4-(trifluoromethyl)anilino]ethanol
• CAS NO: 10442-83-8
• Molecular Formula: C₉H₉F₃N₂O₃
• Molecular Weight: 250.17
• Mol File: 10442-83-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 78-79 °C
• Boiling Point: 351.5 ºC at 760 mmHg
• Flash Point: 166.4 ºC
• Appearance: /
• Density: 1.486g/cm³
• Vapor Pressure: 1.52E-05mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: 2-8°C
• PKA: 14.54±0.10(Predicted)
• CAS DataBase Reference: HC Yellow 13(CAS DataBase Reference)
• NIST Chemistry Reference: HC Yellow 13(10442-83-8)
• EPA Substance Registry System: HC Yellow 13(10442-83-8)

Safety Data

• Hazardous Substances Data: 10442-83-8(Hazardous Substances Data)

Usage

General Description

HC Yellow 13, also known as Solvent Yellow 98, is a synthetic organic dye used primarily as a coloring agent in a variety of products such as plastics, textiles, and printing inks. It is a yellow powder that is soluble in organic solvents and has good light and heat stability. HC Yellow 13 is known for its high color strength, excellent lightfastness, and low migration properties, making it a popular choice for applications requiring durable and vibrant color. However, due to concerns about its potential toxicity and environmental impact, the use of HC Yellow 13 is tightly regulated in some regions, and alternative, safer colorants are being sought for certain applications.

InChI:InChI=1/C9H9F3N2O3/c10-9(11,12)6-1-2-7(13-3-4-15)8(5-6)14(16)17/h1-2,5,13,15H,3-4H2

Upstream product

• 141-43-5 ethanolamine 
• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 349-03-1 1-bromo-4-trifluoromethyl-2-nitrobenzene 
• 367-86-2 1-fluoro-2-nitro-4-trifluoromethyl-benzene 
• 71-36-3 butan-1-ol 

Downstream Products

• 100418-39-1 2-Nitro-N-(2-thiocyanatoethyl)-4-trifluoromethylaniline 
• 100417-19-4 2-imino-3-(2'-amino-4'-trifluoromethylphenyl)-thiazolidine dihydrochloride 
• 100417-32-1 3-(2-nitro-4-trifluoromethylphenyl)-2-iminothiazolidine hydrochloride 
• 130131-25-8 2-(2-Imino-thiazolidin-3-yl)-5-trifluoromethyl-phenylamine; compound with ethanesulfonic acid 
• 1446091-53-7 N₁-(2-((tert-butyldimethylsilyl)oxy)ethyl)-4-(trifluoromethyl)benzenene-1,2-diamine 
• 1446091-52-6 N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-2-nitro-4-(trifluoromethyl)aniline 
• 911381-06-1 ethyl 3-(4-{2-[2,5-bis(trifluoromethyl)-1H-benzimidazol-1-yl]ethoxy}phenyl)-2-ethoxypropanoate 
• 400-98-6 4-trifluoromethyl-2-nitroaniline 
• 10442-84-9 4-trifluoromethyl-N-(2-hydroxyethyl)-O-phenylenediamine 
• 100418-36-8 Methanesulfonic acid 2-(2-nitro-4-trifluoromethyl-phenylamino)-ethyl ester 

Relevant articles and documents

Combining Flavin Photocatalysis and Organocatalysis: Metal-Free Aerobic Oxidation of Unactivated Benzylic Substrates

We report a system with ethylene-bridged flavinium salt 2b which catalyzes the aerobic oxidation of toluenes and benzyl alcohols with high oxidation potential (Eox > +2.5 V vs SCE) to give the corresponding benzoic acids under visible light irradiation. This is caused by the high oxidizing power of excited 2b (E(2b?) = +2.67 V vs SCE) involved in photooxidation and by the accompanying dark organocatalytic oxygenation provided by the in situ formed flavin hydroperoxide 2b-OOH.

Regulating Cofactor Balance In Vivo with a Synthetic Flavin Analogue

A novel strategy to regulate cofactor balance in vivo for whole-cell biotransformation using a synthetic flavin analogue is reported. High efficiency, easy operation, and good applicability were observed for this system. Confocal laser scanning microscopy was employed to verify that the synthetic flavin analogue can directly permeate into Escherichia coli cells without modifying the cell membrane. This work provides a promising intracellular redox regulatory approach to construct more efficient cell factories.

CONDENSED TRICYCLIC COMPOUNDS AS Raf KINASE INHIBITORS

PROBLEM TO BE SOLVED: To provide specific tricyclic compounds that can be useful for inhibiting Raf kinase and for treating disorders mediated by Raf kinase. SOLUTION: A compound is represented by the general formula 1 in the figure. (Q is C or N; W is C or N; X is CH2 or O; Y is NR12, O or S; Z is O, S, NR13, CO, SO, SO2 or CR13R14; R1 to R6 are each independently hydrogen, halogen, haloalkyl, alkyl or the like.) SELECTED DRAWING: None COPYRIGHT: (C)2017,JPO&INPIT