104432-03-3

Upstream product

• 104432-02-2 Benzoic acid (S)-methoxycarbonyl-((2R,4R,5R,6R)-2-methoxy-5,6-dimethyl-4-phenylselanylmethyl-tetrahydro-pyran-2-yl)-methyl ester 
• 104431-96-1 (3aS,4R,5R,6aS)-4,5-Dimethyl-tetrahydro-furo[2,3-b]furan-2-one 
• 104486-84-2 (-)-(1R,2R,6R,7R)-6,7-dimethyl-3-oxo-2,8-dioxabicyclo[3.3.0]octane 
• 65781-37-5 (2S,3R)-2-Methyl-3-(tetrahydro-pyran-2-yloxy)-butyraldehyde 
• 104431-95-0 (4S,5R,6R)-5,6-Dimethyl-4-nitromethyl-tetrahydro-pyran-2-one 
• 104431-99-4 (S)-((2R,4R,5R,6R)-4-[1,3]Dithiolan-2-yl-2-methoxy-5,6-dimethyl-tetrahydro-pyran-2-yl)-hydroxy-acetic acid methyl ester 
• 104431-99-4 ((2R,4R,5R,6R)-4-[1,3]Dithiolan-2-yl-2-methoxy-5,6-dimethyl-tetrahydro-pyran-2-yl)-hydroxy-acetic acid methyl ester 
• 88635-99-8 (R)-3-((S)-3-Hydroxy-2-methyl-butyryl)-4-isopropyl-oxazolidin-2-one 
• 104431-97-2 (-)-(3R,4R,5R)-4,5-dimethyl-3-(1,3-dithiolan-2-yl)pentanolide 
• 104432-00-0 Benzoic acid (S)-((2R,4R,5R,6R)-4-[1,3]dithiolan-2-yl-2-methoxy-5,6-dimethyl-tetrahydro-pyran-2-yl)-methoxycarbonyl-methyl ester 
• 110134-92-4 Benzoic acid (S)-((2R,4R,5R,6R)-4-formyl-2-methoxy-5,6-dimethyl-tetrahydro-pyran-2-yl)-methoxycarbonyl-methyl ester 
• 104432-01-1 Benzoic acid (S)-((2R,4R,5R,6R)-4-hydroxymethyl-2-methoxy-5,6-dimethyl-tetrahydro-pyran-2-yl)-methoxycarbonyl-methyl ester 
• 110134-91-3 ((2R,4R,5R,6R)-4-[1,3]Dithiolan-2-yl-2-hydroxy-5,6-dimethyl-tetrahydro-pyran-2-yl)-(1-methoxy-1-methyl-ethoxy)-acetic acid methyl ester 
• 104431-98-3 ((2R,4R,5R,6R)-4-[1,3]Dithiolan-2-yl-2-methoxy-5,6-dimethyl-tetrahydro-pyran-2-yl)-oxo-acetic acid methyl ester 

Downstream Products

• 104432-04-4 Benzoic acid (S)-chlorocarbonyl-((2R,4S,5R,6R)-2-methoxy-5,6-dimethyl-4-phenylselanylmethyl-tetrahydro-pyran-2-yl)-methyl ester 
• 111194-21-9 (+/-)-pederin dibenzoate 
• 104432-05-5 C₄₅H₅₇NO₁₁Se 
• 87045-91-8 C₄₅H₅₉NO₁₁Se 
• 87045-91-8 C₄₅H₅₉NO₁₁Se 
• 27973-72-4 (+/-)-pederin 
• 104432-05-5 C₄₅H₅₇NO₁₁Se 
• 87045-91-8 (αS,2R,4R,5R,6R)-N-<(R)-<(2S,4R,6R)-4-(benzoyloxy)-6-<(S)-2,3-dimethoxypropyl>-tetrahydro-5,5-dimethyl-2H-pyran-2-yl>methoxymethyl>-α-(benzoyloxy)tetrahydro-2-methoxy-5,6-dimethyl-4-<(phenylseleno)methyl>-2H-pyran-2-acetamide 
• 87045-91-8 (αS,2R,4R,5R,6R)-N-<(S)-<(2S,4R,6R)-4-(benzoyloxy)-6-<(S)-2,3-dimethoxypropyl>-tetrahydro-5,5-dimethyl-2H-pyran-2-yl>methoxymethyl>-α-(benzoyloxy)tetrahydro-2-methoxy-5,6-dimethyl-4-<(phenylseleno)methyl>-2H-pyran-2-acetamide 
• 104432-04-4 Benzoic acid (S)-chlorocarbonyl-((2R,4R,5R,6R)-2-methoxy-5,6-dimethyl-4-phenylselanylmethyl-tetrahydro-pyran-2-yl)-methyl ester 

Relevant academic research and scientific papers

STUDIES RELATED TO THE SYNTHESIS OF (+/-)-PEDERIN. PART 1. SYNTHESIS OF ETHYL PEDERATE AND BENZOYLSELENOPEDERIC ACID.

The first in a series of 2 papers on the synthesis of the insect toxin pederin (1) begins with a discussion of synthesis of the ring A fragments (+/-) pederate (2) and (+/-)-benzoylselenopederic acid (4).A silicon-mediated intramolecular cyclisation of a

The Total Synthesis of (+/-)-Pederin

The conjugate addition of phenylselenomethyl-lithium to the α,β-unsaturated lactone (4) was a key step in a short synthesis of (+/-)-benzoylselenopederic acid (2); union of (2) and (+/-)-benzoylpedamide (3) by a modification of known procedures gave (+/-)-pederin (1).