104436-06-8

Basic information

• Product Name: methyl 4-<<6-(2-ethylhexanamido)indol-1-yl>methyl>benzoate
• Synonyms: methyl 4-<<6-(2-ethylhexanamido)indol-1-yl>methyl>benzoate
• CAS NO: 104436-06-8
• Molecular Weight: 406.525
• Mol File: 104436-06-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-<<6-(2-ethylhexanamido)indol-1-yl>methyl>benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-<<6-(2-ethylhexanamido)indol-1-yl>methyl>benzoate(104436-06-8)
• EPA Substance Registry System: methyl 4-<<6-(2-ethylhexanamido)indol-1-yl>methyl>benzoate(104436-06-8)

Safety Data

• Hazardous Substances Data: 104436-06-8(Hazardous Substances Data)

Upstream product

• 104436-05-7 6-(2-ethylhexanamido)indole 
• 4769-96-4 6-nitroindole 
• 5318-27-4 6-amino-1H-indole 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 

Downstream Products

• 104437-29-8 N-(4-[6-(2-ethylhexanamido)indol-1-ylmethyl]benzoyl)benzenesulphonamide 
• 104436-36-4 4-[6-(2-Ethyl-hexanoylamino)-indol-1-ylmethyl]-benzoic acid 

Relevant articles and documents

Indazole compounds, pharmaceutical compositions and use

The invention provides a series of novel heterocyclic amides of the formula I in which the group A CRa can be --CRb=CRa--, --CHRb--CHRa-- or --N=CRa--, the amidic group Re.L can be Re.X.CO.NH, Re.X.CS.NH or Re.NH.CO attached at position 4, 5 or 6 of the benzenoid moiety, Z is an acid group selected from the group consisting of carboxy, an acylsulphonamide residue of the formula CO.NH.SOn Rg and a tetrazolyl residue of the formula II, and the radicals Ra, Rb, Rc, Rd, Re, Rf, Rg, Rh, n, X, G1, Q and G2 have the meanings defined in the following specification. The compounds of formula I are leukotriene antagonists. The invention also provides pharmaceutically acceptable salts of the formula I compounds; pharmaceutical compositions containing the formula I compounds, or their salts, for use in the treatment of, for example, allergic or inflammatory diseases, or endotoxic or traumatic shock conditions; and processes for the manufacture of the formula I compounds, as well as intermediates for use in such manufacture.