10444-60-7

Upstream product

• 126256-55-1 N¹-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-tetrazole-1,5-diamine 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1132-77-0 (4-chloro-benzylidene)-carbonohydrazonic acid dibromide 
• 71141-20-3 Benzoic acid N'-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-N-methyl-hydrazide 
• 61199-69-7 5-[(4-chloro-benzylidene)-hydrazino]-3-methyl-2-phenyl-[1,3,4]thiadiazolium betaine 
• 71141-14-5 5-[(4-chloro-benzylidene)-hydrazino]-2,3-diphenyl-[1,3,4]thiadiazolium betaine 
• 71141-08-7 5-[(4-chloro-benzylidene)-hydrazino]-3-methyl-2-phenyl-[1,3,4]thiadiazolium; bromide 
• 71141-10-1 5-[(4-chloro-benzylidene)-hydrazino]-2,3-diphenyl-[1,3,4]thiadiazolium; bromide 
• 61199-66-4 4-chloro-benzaldehyde (10-methyl-6,8-dioxo-4,7-diphenyl-dihydro-1,4-epiazano-[1,2,4]triazolo[1,2-c][1,3,4,5]thiatriazin-2-ylidene)-hydrazone 

Relevant academic research and scientific papers

CYSTATHIONINE-Υ-LYASE (CSE) INHIBITORS

Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine -γ-lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.

Dimroth Rearrangement of Imines Derived from 1,5-Diaminotetrazole

Heating the imines 1 in dimethyl sulfoxide (or partly in xylene) provides hydrazones such as 2.The reaction is greatly favoured by electron-withdrawing groups attached to the imine carbon atom.