1044506-40-2Relevant academic research and scientific papers
Synthesis, photochromic properties, and light-controlled metal complexation of a naphthopyran derivative
Kumar, Satish,Hernandez, David,Hoa, Brenda,Lee, Yuna,Yang, Julie S.,McCurdy, Alison
supporting information; experimental part, p. 3761 - 3764 (2009/07/09)
(Chemical Equation Presented) A light-controlled reversible binding switch based on photochromic 3H-naphtho[2,1-b]pyran is under development for studying cellular oscillatory calcium signals. The binding affinities of the closed and open forms of substituted naphthopyran 1 for Ca2+, Mg2+, and Sr2+ in buffer were determined. The photochemically ring-opened form of the receptor exhibited increased affinity compared to the thermally stable closed form of the receptor. The binding affinity difference for Ca 2+ was ～77-fold at pH 7.6.
