104458-33-5 Usage
Uses
Used in Pharmaceutical Industry:
3-aminopropane-1-sulfonamide hydrochloride is used as an intermediate in the synthesis of pyrrolopyridinylbenzenesulfonamide compounds for their IKK2 inhibitory properties. These IKK2 inhibitors are valuable in the development of drugs targeting various diseases and conditions, particularly those involving inflammatory and immune responses. By inhibiting IKK2, these compounds can potentially modulate the activity of signaling pathways and offer therapeutic benefits in treating related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 104458-33-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,4,5 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 104458-33:
(8*1)+(7*0)+(6*4)+(5*4)+(4*5)+(3*8)+(2*3)+(1*3)=105
105 % 10 = 5
So 104458-33-5 is a valid CAS Registry Number.
104458-33-5Relevant academic research and scientific papers
A kind of IDO inhibitor and use thereof
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Paragraph 0333-0334; 0342-0343, (2019/07/11)
The embodiment of the invention provides general formula (I) compound or its pharmaceutically acceptable salts, stereoisomers, a tautomeric form each other, polymorphs, solvate, prodrug, metabolite or isotope derivatives, wherein the substituents R1