1044746-98-6 Usage
Description
Topotecan-d6 Hydrochloride is a labeled analogue of Topotecan Hydrochloride, a semisynthetic derivative of Camptothecin and a potent DNA topoisomerase I inhibitor. It is an antineoplastic agent used in chemotherapy for its ability to inhibit topoisomerase I, thereby disrupting DNA replication and transcription, leading to the prevention of cancer cell proliferation.
Uses
Used in Oncology:
Topotecan-d6 Hydrochloride is used as a chemotherapy agent for the treatment of various types of cancer. It functions as a topoisomerase 1 inhibitor, which plays a crucial role in DNA replication and transcription. By inhibiting this enzyme, Topotecan-d6 Hydrochloride disrupts the essential processes within cancer cells, ultimately preventing their proliferation and contributing to the reduction of tumor size.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, Topotecan-d6 Hydrochloride serves as an important compound for research and development. Its unique mechanism of action as a topoisomerase I inhibitor makes it a valuable tool for studying the effects of such inhibitors on cancer cells and for developing new anticancer drugs with improved efficacy and reduced side effects.
Used in Drug Synthesis:
Topotecan-d6 Hydrochloride is also utilized in the synthesis of other related compounds and drug candidates. Its semisynthetic nature allows for the exploration of structural modifications and the development of new derivatives with potentially enhanced anticancer properties or improved pharmacokinetic profiles.
Overall, Topotecan-d6 Hydrochloride is a versatile compound with significant applications in the field of oncology, pharmaceutical research, and drug synthesis, making it an essential component in the ongoing fight against cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1044746-98-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,4,7,4 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1044746-98:
(9*1)+(8*0)+(7*4)+(6*4)+(5*7)+(4*4)+(3*6)+(2*9)+(1*8)=156
156 % 10 = 6
So 1044746-98-6 is a valid CAS Registry Number.