1044767-99-8

Basic information

• Product Name: 5-bromo-4-chloropyrimidin-2-amine
• Synonyms: 5-bromo-4-chloropyrimidin-2-amine;5-Bromo-4-chloro-2-pyrimidinamine
• CAS NO: 1044767-99-8
• Molecular Formula: C₄H₃BrClN₃
• Molecular Weight: 208.44372
• Mol File: 1044767-99-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 382.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.960±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.72±0.10(Predicted)
• CAS DataBase Reference: 5-bromo-4-chloropyrimidin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-4-chloropyrimidin-2-amine(1044767-99-8)
• EPA Substance Registry System: 5-bromo-4-chloropyrimidin-2-amine(1044767-99-8)

Safety Data

• Hazardous Substances Data: 1044767-99-8(Hazardous Substances Data)

Usage

General Description

5-bromo-4-chloropyrimidin-2-amine is a chemical compound with the molecular formula C4H3BrClN3. It is a heterocyclic compound that contains a pyrimidine ring with a bromine atom at the 5th position and a chlorine atom at the 4th position. The amine group is located at the 2nd position of the pyrimidine ring. 5-bromo-4-chloropyrimidin-2-amine is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in organic synthesis to create various functionalized pyrimidine derivatives. Additionally, 5-bromo-4-chloropyrimidin-2-amine has been found to have potential biological properties, making it of interest for further research and development in the pharmaceutical industry.

Upstream product

• 3993-78-0 2-amino-4-chloropyrimidine 

Downstream Products

• 948549-60-8 4-benzyloxy-5-bromo-pyrimidin-2-ylamine 
• 1425045-83-5 C₂₁H₁₇BrClN₅O 
• 36082-45-8 5-bromo-4-methoxypyrimidine-2-ylamine 
• 1394120-80-9 5-bromo-4-(6-bromoindazol-1-yl)pyrimidin-2-amine 

Relevant articles and documents

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OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION FOR COMBINATION THERAPY

The present invention relates to combination therapy using compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein and an additional pharmaceutically active agent. The invention also relates to pharmaceutical compositions comprising these combinations, and methods of using these combinations in the treatment of various diseases and disorders.

OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.