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Ethyl 4-chloro-2-cyclopropylpyrimidine-5-carboxylate is a pyrimidine derivative, a class of chemical compounds with a distinctive six-membered heterocyclic aromatic ring. This specific compound is characterized by its white to off-white solid appearance and a molecular formula of C10H10ClN3O2. It is widely recognized for its applications in organic synthesis and medicinal chemistry, where it serves as a crucial building block for the development of pharmaceuticals and agrochemicals. Additionally, it exhibits potential biological activities, such as antifungal and antiviral properties, and is under investigation for its therapeutic potential in treating various diseases, positioning it as a significant compound in pharmaceutical research and development.

1044770-40-2

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1044770-40-2 Usage

Uses

Used in Pharmaceutical and Agrochemical Production:
Ethyl 4-chloro-2-cyclopropylpyrimidine-5-carboxylate is utilized as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a valuable component in the creation of new and effective compounds for medical and agricultural applications.
Used in Organic Synthesis:
In the field of organic synthesis, ethyl 4-chloro-2-cyclopropylpyrimidine-5-carboxylate is employed as a versatile building block. Its chemical properties allow for a range of reactions that can lead to the formation of diverse organic compounds, contributing to the development of novel chemical entities.
Used in Antifungal and Antiviral Applications:
Ethyl 4-chloro-2-cyclopropylpyrimidine-5-carboxylate is recognized for its potential as an antifungal and antiviral agent. Its biological activities make it a candidate for the development of treatments against fungal infections and viral diseases, offering new therapeutic options for patients.
Used in Disease Treatment Research:
ethyl 4-chloro-2-cyclopropylpyrimidine-5-carboxylate is also being studied for its potential use in the treatment of various diseases. Its exploration in pharmaceutical research aims to uncover its therapeutic capabilities, which could lead to the development of new drugs for a range of medical conditions.
Used in Drug Development:
Ethyl 4-chloro-2-cyclopropylpyrimidine-5-carboxylate is a valuable asset in drug development, where its unique properties can be harnessed to create new pharmaceuticals with improved efficacy and safety profiles. Its role in this process is crucial for advancing the field of medicine and providing better treatment options for various health issues.

Check Digit Verification of cas no

The CAS Registry Mumber 1044770-40-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,4,7,7 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1044770-40:
(9*1)+(8*0)+(7*4)+(6*4)+(5*7)+(4*7)+(3*0)+(2*4)+(1*0)=132
132 % 10 = 2
So 1044770-40-2 is a valid CAS Registry Number.

1044770-40-2Downstream Products

1044770-40-2Relevant academic research and scientific papers

Novel inhibitors of AP-1 and NF-κB mediated gene expression: Structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate

Palanki, Moorthy S.S.,Erdman, Paul E.,Manning, Anthony M.,Ow, Arnold,Ransone, Lynn J.,Spooner, Cheryl,Suto, Carla,Suto, Mark

, p. 1645 - 1648 (2007/10/03)

In an effort to identify novel inhibitors of AP-1 and NF-κB mediated transcriptional activation, several analogues of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate (1) were synthesized and tested in two in vitro assays. The 2-(2'-thienyl) substituted compound (11) was identified as the most potent in this series. (C) 2000 Elsevier Science Ltd. All rights reserved.

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