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Nitromifene, also known as the free base of Nitromifene Citrate (E/Z mixture), is a non-steroidal estrogen antagonist with structural similarities to Tamoxifen, a selective estrogen response modifier (SERM). It exhibits anti-estrogenic properties and has potential applications in various fields.

10448-84-7

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10448-84-7 Usage

Uses

Used in Pharmaceutical Industry:
Nitromifene is used as an anti-estrogen for its ability to block estrogen receptors, potentially leading to the treatment of hormone-dependent conditions and diseases.
Additionally, Nitromifene Citrate, a derivative of Nitromifene, is used as a non-steroidal estrogen antagonist for similar applications, taking advantage of its structural resemblance to Tamoxifen to modulate estrogen response.

Check Digit Verification of cas no

The CAS Registry Mumber 10448-84-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,4 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 10448-84:
(7*1)+(6*0)+(5*4)+(4*4)+(3*8)+(2*8)+(1*4)=87
87 % 10 = 7
So 10448-84-7 is a valid CAS Registry Number.
InChI:InChI=1/C27H28N2O4/c1-32-24-13-9-21(10-14-24)26(27(29(30)31)23-7-3-2-4-8-23)22-11-15-25(16-12-22)33-20-19-28-17-5-6-18-28/h2-4,7-16H,5-6,17-20H2,1H3/b27-26-

10448-84-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2-[4-[(Z)-1-(4-methoxyphenyl)-2-nitro-2-phenylethenyl]phenoxy]ethyl]pyrrolidine

1.2 Other means of identification

Product number -
Other names Nitromifeno [INN-Spanish]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10448-84-7 SDS

10448-84-7Upstream product

10448-84-7Downstream Products

10448-84-7Related news

Characterization of mcf 7 breast cancer cell growth inhibition by the antiestrogen Nitromifene (cas 10448-84-7) (CI 628) and selected metabolites07/31/2019

Besides undergoing O-demethylation in vivo the triarylethylene antiestrogen nitromifene [1(4-(2-pyrrolidinylethoxy)phenyl)-1(4-methoxy)-phenyl-2-phenyl-2-nitroethene, 1] undergoes biotransformation via nitroreduction, ethene bond cleavage, and pyrrolidine ring oxidation affording ketone metaboli...detailed

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