1044822-25-4Relevant academic research and scientific papers
Efficient route to 2H-1,3-oxazines through ring expansion of isoxazoles by rhodium carbenoids
Manning, James R.,Davies, Huw M.L.
, p. 6901 - 6908 (2008/09/20)
Studies related to the total synthesis of elisabethin C led to the discovery of a rhodium-catalyzed cascade sequence involving isoxazole ring expansion and a [4+3] cycloaddition. The scope of the isoxazole ring expansion was explored, resulting in the synthesis of a range of 2H-1,3-oxazines in 47-96% yield.
