104483-68-3

Basic information

• Product Name: 1-(2-(trifluoromethyl)phenyl)-3,3-dimethylbutan-2-one
• Synonyms: 1-(2-(trifluoromethyl)phenyl)-3,3-dimethylbutan-2-one
• CAS NO: 104483-68-3
• Molecular Weight: 244.257
• Mol File: 104483-68-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-(trifluoromethyl)phenyl)-3,3-dimethylbutan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(trifluoromethyl)phenyl)-3,3-dimethylbutan-2-one(104483-68-3)
• EPA Substance Registry System: 1-(2-(trifluoromethyl)phenyl)-3,3-dimethylbutan-2-one(104483-68-3)

Safety Data

• Hazardous Substances Data: 104483-68-3(Hazardous Substances Data)

Upstream product

• 75-97-8 3,3-dimethyl-butan-2-one 
• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 
• 444-29-1 2-iodo(trifluoromethyl)benzene 

Relevant articles and documents

Palladium-catalyzed α-ketone arylation under mild conditions

The α-arylation of ketones with aryl halides catalyzed by the easily prepared and air-stable palladium complex (SIPr)Pd(Py)Cl2 (3) is described. Complex 3 displays high activity for a variety of aryl halides (activated, unactivated, and sterically hindered aryl halides) under mild conditions. Moreover, both aryl and alkyl ketones can be arylated. The α-arylation of some alkyl ketones can even be run at room temperature. The mono- or diarylated products of the unhindered dialkyl ketone 3-pentanone could be controlled by temperature and the ratio of ketones to aryl halides. Palladium-catalyzed α-ketone arylation of aryl and alkyl ketones with aryl halides is described. A total of 31 examples is presented with yields ranging from 45 to 95%.The mono- or diarylated product of the unhindered dialkyl ketone 3-pentanone could be controlled. Copyright