1044872-40-3Relevant articles and documents
METHOD FOR PRODUCING TRIAZOLOPYRIDINE COMPOUND
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Paragraph 0223-0226, (2020/11/30)
The present invention relates to a novel method for producing a triazolopyridine compound or a salt thereof having a PHD inhibitory action and useful for treating or preventing diseases caused by decreased production of EPO, or the like. The present invention provides a method for producing 2-({[7-hydroxy-5-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]carbonyl}amino)acetic acid comprising a step of reacting Compound [VI]: wherein R61, R62 and R111 are as defined in the specification, or a salt thereof.
COMPOUNDS AND METHODS OF USE
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Paragraph 0213, (2015/07/16)
This disclosure provides compounds and compositions and methods of using those compounds and compositions to treat diseases and disorders associated with excessive transforming growth factor-beta (TGFβ) activity. This disclosure also provides methods of using the compounds in combination with one or more cancer immunotherapies.
TREATMENT OF DISEASES BY EPIGENETIC REGULATION
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Paragraph 0424, (2013/11/05)
The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of diseases or disorders that are susceptible to administration of a BET inhibitor.