104513-86-2

Usage

Uses

Used in Pharmaceutical Industry:
Bayogenin 3-O-β-D-glucopyranoside is used as a potential therapeutic agent for various conditions due to its anti-inflammatory, anti-cancer, and antifungal properties. Its presence in traditional herbal medicines highlights its historical use and potential for modern pharmaceutical applications.
Used in Cancer Treatment:
In the field of oncology, Bayogenin 3-O-β-D-glucopyranoside is used as a potential anti-cancer agent, targeting a variety of cancer types. Its mechanism of action may involve the modulation of cellular processes that contribute to tumor growth and progression.
Used in Antifungal Applications:
Bayogenin 3-O-β-D-glucopyranoside is used as an antifungal agent, leveraging its natural properties to combat fungal infections, which can be particularly useful in the development of new antifungal drugs.
Used in Diabetes Treatment:
In the context of diabetes management, Bayogenin 3-O-β-D-glucopyranoside is used as a potential therapeutic agent to help regulate blood sugar levels and improve the overall health of individuals with diabetes.
Used in Cardiovascular Disease Management:
For cardiovascular diseases, Bayogenin 3-O-β-D-glucopyranoside is used as a potential agent to improve heart health and reduce the risk of related complications, given its potential impact on inflammation and other disease processes.
These applications underscore the versatility and potential of Bayogenin 3-O-β-D-glucopyranoside as a natural product with significant medicinal value across different areas of healthcare.

Upstream product

• 1191300-14-7 β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-{[β-D-apio-D-furanosyl-(1->3)]-4-O-(9-oxo-16-β-[(D-xylopyranosyl)oxy]hexadecanoyl)}-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-11-4 β-D-xylopyranosyl-(1->4)-[α-L-rhamnopyranosyl-(1->3)]-α-L-rhamnopyranosyl-(1->2)-[α-L-arabinopyranosyl-(1->3)]-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-10-3 β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-[β-D-apio-D-furanosyl-(1->3)]-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-09-0 β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-[α-L-arabinopyranosyl-(1->3)]-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 162901-83-9 3-O-β-D-glucopyranosyl bayogenin-28-O-β-D-glucopyranosyl ester 

Downstream Products

• 465-00-9 bayogenin 

Relevant academic research and scientific papers

Five new triterpene saponins from Pulsatilla patens var. multifida

Five new oleanane-type glycosides (1-5), along with two known triterpene saponins, were isolated from the roots of Pulsatilla patens var. multifida (Ranunculaceae). The structures of the new triterpene saponins were elucidated as 3-O-β-D-glucopyranosyl(1→2)-β-D-galactopyranosyl hederagenin 28-O-β-D-glucopyran, osyl ester (1), hederagenin 3-O-[β-D- glucopyranosyl(1→2)][β-D-glucopyranosyl(1→6)]-β-D-galactopyranoside (2), 3-O-β-D-glucopyranosyl bayogenin 28-O-α-L-rhamnopyranosyl(1→4)-β-D- glucopyranosyl(1→6)-β-D glucopyranosyl ester (3), 3-O-β-D- glucopyranosyl(1→2)-β-D-galactopyranosyl oleanolic acid 28-O-α-L- rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6):β-D-glucopyranosyl ester (4), and 3-O-[β-D-glucopyranosyl(1→2)][β-D-glucopyranosyl(1→6)]-β-D- galactopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl(1→4)-β-n- glucopyranosyl(1→6)'β-D-glucopyranosyl ester (5). Structure elucidation was accomplished by 1D and 2D NMR (HMQC, HMBC, and ROESY) methods, FABMS, and hydrolysis.

New triterpenoid saponin glycosides from the fruit fibers of: Trichosanthes cucumerina L.

Five new triterpenoid saponin glycosides, trichocucumerisides A-E (1-5), together with eleven known compounds (6-16) were isolated from Trichosanthes cucumerina fruit fibers. The structures of the new compounds were elucidated by detailed analysis of NMR and mass spectroscopic data as well as chemical reactions. The anti-inflammatory study against nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells shows that compounds 7 and 9 exhibited stronger NO inhibitory activity, with IC50 values of 3.0 and 2.7 μM, respectively, with comparison to positive references Celecoxib and aminoguanidine (IC50 values 75.7 and 75.0 μM, respectively). Compounds 7 and 9 also possessed a greater selectivity index (SI) of approximately 3-4-fold activity than that of the positive references.

Oleanane saponins from Bellis sylvestris Cyr. and evaluation of their phytotoxicity on Aegilops geniculata Roth

Six oleanane saponins were isolated for the first time from leaves of Bellis sylvestris Cyr., the southern daisy. Their structures were established by the extensive use of 2D-NMR experiments, including COSY, TOCSY, NOESY, HSQC, HMBC, CIGAR, H2BC, and HSQC-TOCSY, along with Q-TOF HRMS2 analysis. All of the compounds are constituted by bayogenin as aglycone, and characterized by the presence of an oligosaccharide moiety, consisting of two to four sugar unities esterified at the C-28 carboxyl carbon. One of the isolated compounds is a bisdesmoside containing an additional sugar moiety at the C-3 carbon. The phytotoxic activity assayed against Aegilops geniculata Roth., a coexisting test species, has been evaluated revealing that all the compounds, at the highest concentrations, showed strong phytotoxicity against the leaf development.

Cytotoxic 16-β-[(d-xylopyranosyl)oxy]oxohexadecanyl triterpene glycosides from a Malagasy plant, Physena sessiliflora

Brine shrimp lethality assay-guided separation of the MeOH extract of leaves of Physena sessiliflora, which is endemic to Madagascar, afforded eight triterpene glycosides, Physenoside S1-4 and 16-β-[(d-xylopyranosyl)oxy]oxohexadecanyl homologues, Physenos

Phenolic and triterpenoid glycosides from Aster batangensis

A new phenolic glycoside, asterbatanoside A [p-hydroxyacetophenone-4-O-β-D-xylopyranosyl-(1 → 6)-β-D-glucopyranoside], and two new triterpenoid saponins, asterbatanoside B [2α,3β,23-trihydroxyolean-12-en-28-oic acid-28-O-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranoside] and asterbatanoside C [3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28- oicacid-28-O-β-D-glucopyranoside] were isolated from the roots of Aster batangensis. Their structures were determined by spectroscopic methods and chemical evidence. The total synthesis of asterbatanoside A is also reported. Copyright

New triterpenoid saponins, asterbatanoside D and E, from Aster batangensis

Two new triterpenoid saponins named asterbatanoside D and E have been isolated from Aster batangensis and their structures elucidated as 3-O-β-D-glucopyranosyl-bayogenin-28-O-β-D-glucopyranosyl (1→6)-β-D-glucopyranoside and 3-O-6'-acetyl-β-D-glucopyranosyl-bayogenin-28-O-β-D-glucopyranosyl-( 1→6)-β-D-glucopyranoside by means of MS, 1D and 2D NMR techniques (COSY, TOCSY, ROESY, HMQC, and HMBC), and chemical reactions.