104514-49-0

Usage

Uses

Used in Pharmaceutical Industry:
1,2-DIBROMO-3-CHLORO-BENZENE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the formation of complex organic molecules required for drug development.
Used in Agrochemical Industry:
In the agrochemical sector, 1,2-DIBROMO-3-CHLORO-BENZENE serves as a starting material for the production of various agrochemicals, contributing to the development of effective pest control agents and other agricultural products.
Used in Chemical Production:
1,2-DIBROMO-3-CHLORO-BENZENE is utilized as a starting material for the production of other chemicals, such as dyes, polymers, and fragrances, due to its versatile chemical properties and reactivity in various chemical reactions.
It is crucial to handle and use 1,2-DIBROMO-3-CHLORO-BENZENE with proper safety precautions and protective equipment to prevent any potential health hazards associated with its harmful effects when swallowed, inhaled, or exposed to the skin or eyes.

InChI:InChI=1/C6H3Br2Cl/c7-4-2-1-3-5(9)6(4)8/h1-3H

Upstream product

• 24108-97-2 3,4-dibromoacetanilide 
• 108-37-2 1-bromo-3-chlorobenzene 

Downstream Products

• 93224-85-2 2-bromo-6-chlorobenzoic acid 
• 56961-26-3 2-bromo-3-chlorobenzoic acid 
• 16932-45-9 1-bromo-2,6-dimethoxybenzene 
• 1267964-61-3 2'-bromo-2,6,2'',6''-tetramethoxy-[1,1';3',1'']terphenyl 
• 108-37-2 1-bromo-3-chlorobenzene 
• 694-80-4 2-bromo-1-chlorobenzene 

Relevant academic research and scientific papers

Efficient and complementary methods offering access to synthetically valuable 1,2-dibromobenzenes

1,2-Dibromobenzenes are highly valuable precursors for various organic transformations, in particular, reactions based on the intermediate formation of benzynes. This report describes short sequences for the synthesis of various derivatives based on regioselective bromination, ortho-metalation, and halogen/metal permutations. 1,2-Dibromo-3-iodobenzene (2f), 1,2-dibromo-4- iodobenzene (4c), and 2,3-dibromo-1,4-diiodobenzene (5e) act as intermediates in these syntheses. Bromo-iodoarenes have been synthesized by short and regioselective bromination or iodination sequences that combine ortho-metalation, halo-desilylation, diazotation, or bromination reactions of anilines. These polyhalo derivatives were then used as key intermediates to access a wide range of functionalized 1,2-dibromobenzenes by chemoselective organometallic reactions. Copyright

An improved method for the bromination of metalated haloarenes via lithium, zinc transmetalation: A convenient synthesis of 1,2-dibromoarenes

A facile protocol for the synthesis of 1,2-dibromoarenes is described. A standard ortho-lithiation/bromination procedure, when applied to bromoarenes, resulted in poor yields of the corresponding 1,2-dibromoarenes (13-62% yield). However, transmetalation