104516-53-2Relevant academic research and scientific papers
β-cyclodextrin (β-CD) as a supramolecular catalyst for the synthesis of isoxazoles and thiopyrimidines and their antimicrobial screening
Chate, Asha V.,Gill, Charansingh H.
, p. 93 - 102 (2017/03/30)
Background: Isoxazole and pyrimidines are interesting heterocyclic molecules, which are present as structural motif in numerous natural products synthetic drugs. Isoxazole and thiopyrimidines exhibit antidiabetic, cytotoxic tuberculostatic, and anticonvul
Synthesis of α-azido-2′-hydroxychalcones from chalcone dibromides with azide ion
Patonay, Tamas,Jekoe, Jozsef,Riman, Eva
, p. 2403 - 2415 (2007/10/03)
The reaction of the 2′-hydroxychalcone dibromides with azide ion was found to afford various products such as α-azido-2′-hydroxychalcones, flavones, aurones, isoxazoles or the parent chalcones depending on the substituent pattern of the substrate. Efficie
PYRAZOLES AND ISOXAZOLES DERIVED FROM 2-HYDROXYARYL PHENYLETHYNYL KETONES: SYNTHESIS AND SPECTROPHOTOMETRIC EVALUATION OF THEIR POTENTIAL APPLICABILITY AS SUNSCREENS
Garcia, Heremengildo,Iborra, Sara,Miranda, Miguel A.,Morera, Isabel M.,Primo, Jaime
, p. 1745 - 1755 (2007/10/02)
Reaction of the acetylenic ketones (1) with hydrazine or hydroxylamine leads to the pyrazoles (2) or the isoxazoles (3), respectively.Spectrophotometric evaluation of the UV-photoprotecting ability as compared to p-aminobenzoic acid (PABA) shows that the predicted effectiveness of 2 and the 3-phenylisoxazoles (3B) is very close to that of PABA, while that of the 5-phenylisoxazoles (3A) is clearly lower.The pyrazoles (2) are more stable than PABA upon UV-irradiation in cyclohexane solution.
BENZO-γ-PYRONES, PART XIV. REACTION OF C-SUBSTITUTED 2-PHENYL-4H-1-BENZOPYRAN-4-ONES WITH HYDROXYLAMINE
Basinski, Wlodzimierz
, p. 1619 - 1632 (2007/10/02)
The reaction of C-6,7,8 (CH3, Br) and C-4' (OCH3) substituted flavones 1a-1f with hydroxylamine in anhydrous pyridine has been investigated.The oximes 2a-2f and isoxazoles 3a-3f were obtained.It has been established that the ratio of oxime to isoxazole de
