104517-01-3

Upstream product

• 4397-53-9 p-benzyloxybenzaldehyde 
• 90-05-1 2-methoxy-phenol 
• 84184-52-1 (E)-3-(4-(benzyloxy)phenyl)prop-2-en-1-ol 
• 87030-11-3 ethyl 3-(4-(benzyloxy)phenyl)acrylate 
• 87030-12-4 4-benzyloxycinnamyl alcohol 

Downstream Products

• 104315-06-2 4-[(E)-3-(4-Benzyloxy-phenyl)-allyl]-2-methoxy-phenol 
• 97456-01-4 rac-6-(4-benzyloxy-α-vinylbenzyl)guiacol 
• 97456-04-7 rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>phthalimide 
• 97456-08-1 rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide 
• 97455-98-6 rac-di-O-benzyl-latifine 
• 97456-06-9 rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>formamide 
• 97456-07-0 rac-2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxy-N-methylphenethylamine 
• 97456-03-6 rac-2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl alcohol 
• 97456-05-8 rac-2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethylamine 
• 97549-48-9 (+/-)-latifine 
• 97455-99-7 5-Benzyloxy-4-(4-benzyloxy-phenyl)-6-methoxy-2-methyl-3,4-dihydro-isoquinolinium; chloride 
• 97456-02-5 rac-3-(4-benzyloxyphenyl)-3-(2-benzyloxy-3-methoxyphenyl)prop-1-ene 

Relevant academic research and scientific papers

THE TOTAL SYNTHESIS OF (+/-)-LATIFINE

Latifine, a novel phenolic isoquinoline base from Crinum latifolium L. (Amaryllidaceae), has been synthesized.

Total Synthesis of (+/-)- and (+)-Latifine

Racemic latifine (+)-(1), a new representative of the rare phenolic Amaryllidaceae alkaloids, has been synthesized by employing the Claisen rearrangement of 4-benzyloxycinnamyl 2-methoxyphenyl ether (11) as a key step.Based on the racemic synthesis, (R)-(