104528-83-8

Basic information

• Product Name: L-Tyrosine, 3-Methoxy-O-Methyl-, ethyl ester
• Synonyms: L-Tyrosine, 3-Methoxy-O-Methyl-, ethyl ester
• CAS NO: 104528-83-8
• Molecular Formula: C₁₃H₁₉NO₄
• Molecular Weight: 253.29426
• Mol File: 104528-83-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Tyrosine, 3-Methoxy-O-Methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tyrosine, 3-Methoxy-O-Methyl-, ethyl ester(104528-83-8)
• EPA Substance Registry System: L-Tyrosine, 3-Methoxy-O-Methyl-, ethyl ester(104528-83-8)

Safety Data

• Hazardous Substances Data: 104528-83-8(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 32161-30-1 (S)-3,4-dimethoxyphenylalanine 
• 23234-41-5 2-Amino-3-(3,4-dihydroxy-phenyl)-propionic acid ethyl ester; hydrochloride 
• 59-92-7 3,4-dihydroxy-L-phenylalanine 
• 128217-61-8 2-tert-Butoxycarbonylamino-3-(3,4-dimethoxy-phenyl)-propionic acid ethyl ester 

Downstream Products

• 128217-65-2 2-Allyloxycarbonylamino-3-(3,4-dimethoxy-phenyl)-propionic acid ethyl ester 
• 372965-64-5 (S)-N-(4-methylpent-3-enyl)-3-(3,4-dimethoxyphenyl)alanine ethyl ester 
• 372965-67-8 (S)-N-benzyl-3-(3,4-dimethoxyphenyl)-N-(4-methylpent-3-enyl)alaninal 
• 372965-66-7 (S)-N-benzyl-3-(3,4-dimethoxyphenyl)-N-(4-methylpent-3-enyl)alaninol 
• 372965-70-3 (1S,4aR,10aS)-1-(3,4-dimethoxybenzyl)-1,2,3,4,4a,5,10,10a-octahydro-5,5-dimethylbenzo[b][1,7]naphthyridine 
• 372965-71-4 (1S,4aS,10aS)-1-(3,4-dimethoxybenzyl)-1,2,3,4,4a,5,10,10a-octahydro-5,5-dimethylbenzo[b][1,7]naphthyridine 
• 372965-65-6 (S)-N-benzyl-N-(4-methylpent-3-enyl)-3-(3,4-dimethoxyphenyl)alanine ethyl ester 
• 372965-68-9 (1S,4aR,10aS)-2-benzyl-7-chloro-1-(3,4-dimethoxybenzyl)-1,2,3,4,4a,5,10,10a-octahydro-5,5-dimethylbenzo[b][1,7]naphthyridine 
• 372965-69-0 (1S,4aS,10aS)-2-benzyl-7-chloro-1-(3,4-dimethoxybenzyl)-1,2,3,4,4a,5,10,10a-octahydro-5,5-dimethylbenzo[b][1,7]naphthyridine 
• 128217-76-5 2-Allyloxycarbonylamino-3-(4,5-dimethoxy-2-nitro-phenyl)-propionic acid ethyl ester 
• 35149-81-6 N-benzoyl-(S)-3,4-dimethoxyphenylalanine 

Relevant articles and documents

Rh(iii)-Catalyzed diastereoselective transfer hydrogenation: An efficient entry to key intermediates of HIV protease inhibitors

A highly efficient diastereoselective transfer hydrogenation of α-aminoalkyl α′-chloromethyl ketones catalyzed by a tethered rhodium complex was developed and successfully utilized in the synthesis of the key intermediates of HIV protease inhibitors. With the current Rh(iii) catalyst system, a series of chiral 3-amino-1-chloro-2-hydroxy-4-phenylbutanes were produced in excellent yields and diastereoselectivities (up to 99% yield, up to 99?:?1 dr). Both diastereomers of the desired products could be efficiently accessed by using the two enantiomers of the Rh(iii) catalyst.

Synthesis of the Chromophore of Pseudobactin, a Fluorescent Siderophore from Pseudomonas

Protected forms of dihydroxyphenylalanine (DOPA) were converted to the corresponding dihydroquinolin-2-ones 13 by nitration and reductive cyclization.Subsequent N-alkylation with α-halo-γ-aminobutyric acid derivatives provided the carbon framework 12 for the chromophore of pseudobactin.Conversion to protected forms of the fluorescent chromophore 5 was accomplished by reaction of 12 with Lawesson's reagent to produce the corresponding thioamide which was cyclized by reaction with mercuric acetate.