1045345-85-4

Upstream product

• 167688-16-6 1-methoxy-4-(3-phenylprop-2-yn-1-yl)benzene 
• 25855-99-6 1-(4-methylphenyl)-3-phenyl-1,3-propanedione 

Relevant academic research and scientific papers

Propargylation of 1,3-dicarbonyl compounds catalyzed by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone and sodium nitrite in the presence of molecular oxygen and formic acid

Catalyzed by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and sodium nitrite, the coupling reaction of 1,3-diarylpropynes and 1,3-dicarbonyl compounds using molecular oxygen as a terminal oxidant was developed. The reaction was promoted dramatically in

Propargylation of 1,3-dicarbonyl compounds with 1,3-diarylpropynes via oxidative cross-coupling between sp3 C-H and sp3 C-H

(Chemical Equation Presented) A highly efficient oxidative-coupling reaction between diarylpropargylic sp3 C-H and active methylenic sp3 C-H was achieved with DDQ as oxidant. The reaction afforded a direct method for the propargylation of 1,3-dicarbonyl compounds, thus providing a concise synthesis of the corresponding products.