1045346-47-1Relevant academic research and scientific papers
Cu- and Mo-catalysed expedient synthesis of alkynyl-substituted derivatives of 1,2-dihydropyridines, -quinolines and -isoquinolines
Kumaraswamy, Gullapalli,Rambabu, Dasa,Jayaprakash, Neerasa,Rao, Gadde Venkata,Sridhar, Balasubramanian
, p. 4158 - 4164 (2009)
An efficient synthesis of 1,2-dihydroisoquinolines and -quinolines by employing dimethyl acetylenedicarboxylate activated isoquinolines and quinolines in conjuction with the CuC12/Et3N catalytic system is described herein. Furthermor
Gold(III) chloride-catalyzed three-component reaction: A facile synthesis of alkynyl derivatives of 1,2-dihydroquinolines and isoquinolines
Yadav, Jhillu S.,Subba Reddy, Basi V.,Yadav, Nagendra Nath,Gupta, Manoj K.,Sridhar, Balasubramanian
, p. 6857 - 6859 (2008/12/22)
(Chemical Equation Presented) Gold(III) chloride is found to be an effective catalyst for the addition of alkynes on activated quinoline/ isoquinolines to produce a series of alkynyl-substituted 1,2-dihydroquinolines and isoquinolines in a single-step operation. The easy availability of starting materials, convenient synthetic procedure, operational simplicity, and high regioselectivity makes this strategy very useful for the preparation of enyne derivatives of aza-aromatic compounds.
