104537-70-4

Upstream product

• 638-07-3 ethyl (2-chloroaceto)acetate 
• 99-61-6 3-nitro-benzaldehyde 

Downstream Products

• 107812-63-5 2-chloromethyl-3-carboethoxy-5-carbomethoxy-4-(m-nitro-phenyl)-6-methyl-1,4-dihydropyridine 
• 105435-14-1 2-chloromethyl-3,5-dicarboethoxy-4-(3-nitrophenyl)-6-methyl-1,4-dihydropyridine 
• 121236-58-6 (3S,4R)-2-[1-Chloro-meth-(Z)-ylidene]-6-methyl-4-(3-nitro-phenyl)-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester 
• 121223-51-6 C₁₈H₁₈⁽²⁾HClN₂O₆ 
• 118587-21-6 2-chloromethyl-3-carboethoxy-5-carbomethoxy-4-(m-nitrophenyl)-6-methylpyridine 

Relevant academic research and scientific papers

1,4-dihydropyridines

Dihydropyridines of formula I STR1 wherein R is hydrogen or lower alkyl; R 1 is a CN, NO 2, COCH 3, COPh group, a carboalkoxy or carboamide group; R 2 is an aromatic or heteroaromatic, mono- or bicyclic eventually substituted phenyl group; R 3 is a carboa

Ca(2+)-MODULATORS. UNUSUAL HIGHLY STEREOSPECIFIC HANTZSCH-LIKE CYCLIZATION: FIRST AUTHENTICATED EXAMPLE OF 2-CHLOROMETHYLENE-1,2,3,4-TETRAHYDROPYRIDINE

Hantzsch cyclization of ethyl 4-chloro-2-benzylidene-acetoacetates 5 with methyl 3-aminocrotonate 6 leads to 2-chloromethylene-1,2,3,4-tetrahydropyridine-3,5-dicarboxylic esters 7.X-ray structure analysis and 1H-NMR of 7a established the configuration at

2-(heteroalkyl)-1,4-dihydropyridines, process for their preparations and pharmaceutical compositions containing them

Dihydropyridines of formula I wherein R is hydrogen or lower alkyl; R1 is a CN, NO2, COCH3, COPh group, a carboalkoxy or carboamide group; R2 is an aromatic or heteroaromatic, mono- or bicyclic even-tually subst